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A Deep Learning Toolkit for DTI, Drug Property, PPI, DDI, Protein Function Prediction (Bioinformatics)
Foundation Models for Genomics & Transcriptomics
Precision Medicine Knowledge Graph (PrimeKG)
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Reference mapping for single-cell genomics
Genomic Pretrained Network - GPN, GPN-MSA, PhyloGPN, GPN-Star
MolTrans: Molecular Interaction Transformer for Drug Target Interaction Prediction (Bioinformatics)
scPerturb: A resource and a python/R tool for single-cell perturbation data
Repository for Nicheformer: a foundation model for single-cell and spatial omics
🏃 The go-to single-cell Foundation Model
Code for "Predicting Cellular Responses to Novel Drug Perturbations at a Single-Cell Resolution", NeurIPS 2022.
A collection of tasks to probe the effectiveness of protein sequence representations in modeling aspects of protein design
PRnet is a flexible and scalable perturbation-conditioned generative model predicting transcriptional responses to unseen complex perturbations at bulk and single-cell levels.
BulkFormer: A large-scale foundation model for human bulk transcriptomes
Peax is a tool for interactive visual pattern search and exploration in epigenomic data based on unsupervised representation learning with autoencoders
Machine learning for Analysis of Proteomics in Spatial biology - Nature Communications
Repository for paper scMulan: a multitask generative pre-trained language model for single-cell analysis.
High-Dimensional Gene Expression and Morphology Profiles of Cells across 28,000 Genetic and Chemical Perturbations
CancerFoundation: A single-cell RNA sequencing foundation model to decipher drug resistance in cancer
Deciphering cell-cell communication from spatially resolved transcriptomic data at single-cell resolution with subgraph-based attentional graph neural network
Interpretable drug response prediction with graph neural networks over drugs, cell lines, and genes.