Python GUIs for Humans! Create any GUI simple or complicated in a way that's intuitive. Launched in 2018. NEW for 2026 - the LGPL3 Version 6. Transforms tkinter, Qt, WxPython, and Remi into a simple, intuitive, and fun experience for both hobbyists and expert users.
- pysimplegui
- gui-framework
- python
- tkinter
A keyboard-driven, vim-like browser based on Python and Qt.
Build GUI for your Python program with JavaScript, HTML, and CSS
Provides an uniform layer to support PyQt5, PySide2, PyQt6, PySide6 with a single codebase
ilastik-shell, applets, and workflows to string them together.
Python/PyQt Wacom GUI for KDE
MERK is an open source, cross-platform, multiple-document interface GUI IRC client for Windows, Linux, and macOS written in Python, PyQt5, and Twisted.
- python3
- pyqt5
- gplv3
- irc-client
Push-to-talk voice dictation for Linux. 100% local, multilingual (25+ languages), with speaker diarization. Qt frontend, Rust backend on NVIDIA Parakeet via ONNX Runtime. KDE Plasmoid integrated.