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Python GUIs for Humans! Create any GUI simple or complicated in a way that's intuitive. Launched in 2018. NEW for 2026 - the LGPL3 Version 6. Transforms tkinter, Qt, WxPython, and Remi into a simple, intuitive, and fun experience for both hobbyists and expert users.

  • pysimplegui
  • gui-framework
  • python
  • tkinter

OpenShot Video Editor is an award-winning free and open-source video editor for Linux, Mac, and Windows, and is dedicated to delivering high quality video editing and animation solutions to the world.

Provides an uniform layer to support PyQt5, PySide2, PyQt6, PySide6 with a single codebase

  • python
  • qtpy
  • spyder
  • qt-gui

MERK is an open source, cross-platform, multiple-document interface GUI IRC client for Windows, Linux, and macOS written in Python, PyQt5, and Twisted.

  • python3
  • pyqt5
  • gplv3
  • irc-client

Push-to-talk voice dictation for Linux. 100% local, multilingual (25+ languages), with speaker diarization. Qt frontend, Rust backend on NVIDIA Parakeet via ONNX Runtime. KDE Plasmoid integrated.