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73–96 of 127 · Most stars

Agent-first reverse engineering for macOS, Windows and Linux: any ACP agent reads, renames and patches binaries, Android apps and GPU kernels next to you.

Xiryn — the open-source personal agent. Does everything Muse, Grok Bot and Dots do, on your own computer: each agent gets its own Linux desktop in Docker, any model with your keys, an encrypted vault, and control from Telegram.

An offline-first, self-hosted web app to aggregate and sync all of your medical records from your patient portals in one place.

Morrow is an open source, privacy first, offline workspace note taking app, presented as an alternative to Notion, and other apps!

Your tasks, your server. An open-source, local-first task manager you can host yourself. Everything you expect from a commercial task app, without the subscription or the lock-in.

A local-first study platform for university lectures: PowerPoint slides, spaced repetition, exams, and an optional AI tutor on the Gemini free tier.

OpenScribe is an open-source AI scribe that records patient encounters and generates structured clinical notes automatically. You keep full control over data, workflows, and patient privacy with no vendor lock-in.

  • ai
  • clinical
  • clinical-informatics
  • ehr

Your team of AI agents, on your Mac, Windows or Linux. Agents that talk in channels, write code, review each other and use your tools, on the Claude Code, Codex, OpenCode or Pi you already have. Anything that touches the real world waits for your yes.

Translated研迹 Trail (Yanji, "research trail"): a local-first AI investment research workbench. Connects market quotes, candlestick charts, and deep research, so that judgments are traceable and risks can be reviewed. Local-first AI investment research desktop with an evidence-grounded copilot.