Python GUIs for Humans! Create any GUI simple or complicated in a way that's intuitive. Launched in 2018. NEW for 2026 - the LGPL3 Version 6. Transforms tkinter, Qt, WxPython, and Remi into a simple, intuitive, and fun experience for both hobbyists and expert users.
- pysimplegui
- gui-framework
- python
- tkinter
Build ultra fast, tiny, and cross-platform desktop apps with TypeScript, Zig, Rust, Go, or Odin.
Clipboard manager with advanced features
A single-header ANSI C immediate mode cross-platform GUI library
- c
- gui
- nuklear
- single-header-lib
Simple and portable (but not inflexible) GUI library in C that uses the native GUI technologies of each platform it supports.
A React environment for cross platform desktop apps
Qt binding for Go (Golang) with support for Windows / macOS / Linux / FreeBSD / Android / iOS / Sailfish OS / Raspberry Pi / AsteroidOS / Ubuntu Touch / JavaScript / WebAssembly
- go
- gui-framework
- qt
- cross-platform-gui
High-performance GPGPU inference of OpenAI's Whisper automatic speech recognition (ASR) model
.NET (WPF and Windows Forms) bindings for the Chromium Embedded Framework
- cefsharp
- c-sharp
- c-plus-plus
- wpf
Open-source platform for building cross-platform native Mobile, Web, Desktop, and Embedded apps from a single C#/XAML codebase. Work from any IDE/CLI with Hot Reload, Visual Designer, MCPs, and Skills built for modern .NET workflows. 200M+ NuGet downloads.
GUI image optimizer for Mac
- gui
- image-optimization
- performace
- accelerator
Open source Markdown editor for macOS.
Linux System Optimizer and Monitoring - https://oguzhaninan.github.io/Stacer-Web
- optimizer
- ubuntu
- system-information
- system
WinUI: a modern UI framework with a rich set of controls and styles to build dynamic and high-performing Windows applications.
Platform-native GUI library for Go.
✔️The smallest header-only GUI library(4 KLOC) for all platforms
A tool for defining design systems and using them to generate cross-platform UI code, Sketch files, and other artifacts.
OS.js - JavaScript Web Desktop Platform
- javascript
- cloud-platform
- web-desktop
- desktop
TranslatedFlyingMouse Format (飞鼠格式) - a free file format conversion tool for Windows (works offline, with FFmpeg/LibreOffice/Poppler/Tesseract built in). Converts between image/document/spreadsheet/PPT/PDF/audio-video/WPS formats + OCR + batch conversion; audio supports only common formats. Author: 牢蜂 (LaoFeng, "jailed bee") | For personal free use only; commercial sale, resale, and re-skinning are prohibited
Cross-platform Audio Visualizer
- alsa
- audio-visualizer
- freebsd
- glsl-shaders
😎🏖️🐬 Your new, 𝙧𝙞𝙙𝙤𝙣𝙠𝙪𝙡𝙞𝙘𝙞𝙤𝙪𝙨𝙡𝙮 smart clipboard manager
Flutter on Windows, MacOS and Linux - based on Flutter Embedding, Go and GLFW.
A cross-platform file change monitor with multiple backends: Apple macOS File System Events, *BSD kqueue, Solaris/Illumos File Events Notification, Linux inotify and fanotify, Microsoft Windows and a stat()-based backend.
- event-notifications
- change-monitor
- fswatch
- kqueue
The most popular open source electronic health records and medical practice management solution.
- openemr
- practice-management
- emr
- ehr