Code for "Predicting Cellular Responses to Novel Drug Perturbations at a Single-Cell Resolution", NeurIPS 2022.
- disentanglement
- drug-discovery
- genomics
- perturbation
47,133 repositories indexed
49–72 of 93 · Most stars
Code for "Predicting Cellular Responses to Novel Drug Perturbations at a Single-Cell Resolution", NeurIPS 2022.
TransformerCPI: Improving compound–protein interaction prediction by sequence-based deep learning with self-attention mechanism and label reversal experiments(BIOINFORMATICS 2020) https://doi.org/10.1093/bioinformatics/btaa524
Interpretable bilinear attention network with domain adaptation improves drug-target prediction.
Data visualisation web components for the life sciences.
Accurate and efficient spot detection for microscopy data
A collection of tasks to probe the effectiveness of protein sequence representations in modeling aspects of protein design
A tool for cell instance aware segmentation in densely packed 3D volumetric images
Learning cell communication from spatial graphs of cells
code to run sei and obtain sei and sequence class predictions
CASSIA: A Multi-Agent LLM-Based Single-Cell Cell Type Annotation Framework
Structural variant detection and association testing
Rails frontend to The Genome Institute's drug gene interaction database.
PRnet is a flexible and scalable perturbation-conditioned generative model predicting transcriptional responses to unseen complex perturbations at bulk and single-cell levels.
Toolbox for the analysis of smFISH images.
BulkFormer: A large-scale foundation model for human bulk transcriptomes
NeoDTI: Neural integration of neighbor information from a heterogeneous network for discovering new drug-target interactions
NeuroAnatomy Toolbox: An R package for the (3D) visualisation and analysis of biological image data, especially tracings of single neurons.
PyTorch implementation of the MIDAS algorithm for single-cell multimodal data integration (Nature Biotechnology 2024).
Peax is a tool for interactive visual pattern search and exploration in epigenomic data based on unsupervised representation learning with autoencoders
Machine learning for Analysis of Proteomics in Spatial biology - Nature Communications
Repository for paper scMulan: a multitask generative pre-trained language model for single-cell analysis.
The framework for quantification of neuronal anatomy
Run scripts, explore your genome, and get personalized explanations — all in natural dialogue.
High-Dimensional Gene Expression and Morphology Profiles of Cells across 28,000 Genetic and Chemical Perturbations