The open-source AI research workbench for scientific research and agent workflows. Local-first, model-agnostic desktop app with extensible skills, MCP tools and connectors, Python/R execution and traceable artifacts for reproducible research on macOS, Windows and Linux.
- ai-for-science
- local-first
- reproducible-research
- open-science
Trainable, memory-efficient, and GPU-friendly PyTorch reproduction of AlphaFold 2
- pytorch
- protein-structure
- alphafold2
Plan, apply and roll back changes to a production ontology, with a blast radius report and a proof an auditor can re-check.
- ai-native
- description-logics
- knowledge-graph
- mcp
🦖 ClawBio - The first bioinformatics-native AI agent skill library. Local-first. Reproducible. Open. Free.
Scientific workflow engine designed for simplicity & scalability. Trivially transition between one off use cases to massive scale production environments
Open-source cross-platform symbolic algebra library for C# and F#. Can be used for both production and research purposes.
- csharp
- algebra
- integration
- latex
A Python Package for Protein Dynamics Analysis
The fastest automatic differentiation library for C++, with Python bindings. Forward, adjoint and higher-order derivatives, checkpointing, Eigen support and JIT. Reproducible benchmarks against CppAD, Adept and autodiff.
- automatic-differentiation
- aad
- algorithmic-differentiation
- autodiff
Produce a sharp image of a planetary system object (moon, sun, planets) from many seeing-affected frames according to the "lucky imaging" technique.
Native R and Python sample-deletion robustness for omics: candidate certificates, minimum deletion bounds, Bioconductor model refits and donor-level pseudobulk
ENIGMA HALFpipe is a user-friendly software that facilitates reproducible analysis of fMRI data
- neuroimaging
- reproducibility
- pipeline
- meta-analysis
:dart: Accurate sums and dot products for Python.
UV-first benchmark for protein-ligand docking with reproducible annotation, pocket similarity, and HPC workflows.