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Tags: Bioinformatics
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1–21 of 21 · Most stars

Generation of protein sequences and evolutionary alignments via discrete diffusion models

  • discrete-diffusion
  • generative-model
  • multiple-sequence-alignment
  • protein-sequences

SCENIC is an R package to infer Gene Regulatory Networks and cell types from single-cell RNA-seq data.

A Practical and Efficient NCBI Taxonomy Toolkit, also supports creating NCBI-style taxdump files for custom taxonomies like GTDB/ICTV

Native R and Python sample-deletion robustness for omics: candidate certificates, minimum deletion bounds, Bioconductor model refits and donor-level pseudobulk

Schema and generated objects for biolink data model and upper ontology

  • biolink
  • monarchinitiative
  • gene-ontology
  • datamodel

TransformerCPI: Improving compound–protein interaction prediction by sequence-based deep learning with self-attention mechanism and label reversal experiments(BIOINFORMATICS 2020) https://doi.org/10.1093/bioinformatics/btaa524

  • self-attention
  • compound-protein-interaction
  • transformercpi
  • structure-free-virtual-sreening

A collection of tasks to probe the effectiveness of protein sequence representations in modeling aspects of protein design

  • protein
  • protein-sequences
  • protein-design
  • representation-learning