1.Biohub / esm
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Ranked by Attention Score: stars gained over the last 180 complete days
24 repositories by Attention Score · May 9, 2026 – Nov 4, 2026 (UTC)
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Precision Medicine Knowledge Graph (PrimeKG)
Foundation Models for Genomics & Transcriptomics
A Deep Learning Toolkit for DTI, Drug Property, PPI, DDI, Protein Function Prediction (Bioinformatics)
Genomic Pretrained Network - GPN, GPN-MSA, PhyloGPN, GPN-Star
BulkFormer: A large-scale foundation model for human bulk transcriptomes
ProtTrans is providing state of the art pretrained language models for proteins. ProtTrans was trained on thousands of GPUs from Summit and hundreds of Google TPUs using Transformers Models.
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A collection of tasks to probe the effectiveness of protein sequence representations in modeling aspects of protein design
MolTrans: Molecular Interaction Transformer for Drug Target Interaction Prediction (Bioinformatics)
scPerturb: A resource and a python/R tool for single-cell perturbation data
Repository for Nicheformer: a foundation model for single-cell and spatial omics
🏃 The go-to single-cell Foundation Model
Code for "Predicting Cellular Responses to Novel Drug Perturbations at a Single-Cell Resolution", NeurIPS 2022.
PRnet is a flexible and scalable perturbation-conditioned generative model predicting transcriptional responses to unseen complex perturbations at bulk and single-cell levels.
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Reference mapping for single-cell genomics
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Pan-Cancer Integrative Histology-Genomic Analysis via Multimodal Deep Learning - Cancer Cell
Official repo for CellPLM: Pre-training of Cell Language Model Beyond Single Cells.