1.google-deepmind / mujoco
Multi-Joint dynamics with Contact. A general purpose physics simulator.
+2,766 stars
from 13,294 · score 7.93
Trending repositories
Ranked by Attention Score: stars gained over the last 180 complete days
75 repositories by Attention Score · May 9, 2026 – Nov 4, 2026 (UTC)
2.Genesis-Embodied-AI / genesis-world
Simulation platform for general-purpose robotics & embodied AI learning.
+1,707 stars
from 28,468 · score 7.44
3.google-research / google-research
Google Research
+1,402 stars
from 37,710 · score 7.25
4.chubin / wttr.in
:partly_sunny: The right way to check the weather
- weather-information
- weather-api
- curl
- weather
- weather-app
- terminal
- +1 more
+1,352 stars
from 29,387 · score 7.21
5.tracel-ai / burn
Burn is a next generation tensor library and Deep Learning Framework that doesn't compromise on flexibility, efficiency and portability.
- autodiff
- deep-learning
- machine-learning
- rust
- scientific-computing
- ndarray
- +12 more
+1,333 stars
from 14,901 · score 7.20
6.jax-ml / jax
Composable transformations of Python+NumPy programs: differentiate, vectorize, JIT to GPU/TPU, and more
+1,198 stars
from 35,379 · score 7.09
7.google / or-tools
Google's Operations Research tools:
- combinatorial-optimization
- linear-programming
- operations-research
- optimization
- or-tools
+931 stars
from 13,397 · score 6.84
+828 stars
from 7,898 · score 6.72
9.Project-MONAI / MONAI
AI Toolkit for Healthcare Imaging
- healthcare-imaging
- deep-learning
- medical-image-computing
- medical-image-processing
- pytorch
- python3
- +1 more
+746 stars
from 8,081 · score 6.62
10.Qiskit / qiskit
Qiskit is an open-source SDK for working with quantum computers at the level of extended quantum circuits, operators, and primitives.
- quantum-computing
- qiskit
- sdk
- quantum-programming-language
- quantum-circuit
- quantum
- +3 more
+654 stars
from 7,299 · score 6.48
+451 stars
from 14,477 · score 6.11
12.PennyLaneAI / pennylane
PennyLane is an open-source quantum software platform for quantum computing, quantum machine learning, and quantum chemistry. Create meaningful quantum algorithms, from inspiration to implementation.
+359 stars
from 3,160 · score 5.89
13.mesa / mesa
Mesa is an open-source Python library for agent-based modeling, ideal for simulating complex systems and exploring emergent behaviors.
- mesa
- agent-based-modeling
- agent-based-simulation
- simulation-framework
- simulation
- simulation-environment
- +5 more
+344 stars
from 3,595 · score 5.84
14.google / draco
Draco is a library for compressing and decompressing 3D geometric meshes and point clouds. It is intended to improve the storage and transmission of 3D graphics.
- point-cloud
- 3d-graphics
- compression
- mesh
+307 stars
from 7,234 · score 5.73
15.cvxpy / cvxpy
A Python-embedded modeling language for convex optimization problems.
- python
- cvxpy
- optimization
- modeling-language
- convex-optimization
- mathematical-optimization
- +2 more
+208 stars
from 6,178 · score 5.34
16.quantumlib / Cirq
Python framework for creating, editing, and running Noisy Intermediate-Scale Quantum (NISQ) circuits.
- nisq
- quantum-algorithms
- quantum-computing
- cirq
- algorithms
- api
- +14 more
+176 stars
from 4,924 · score 5.18
17.the-dual-space / pymoo
NSGA2, NSGA3, R-NSGA3, MOEAD, Genetic Algorithms (GA), Differential Evolution (DE), CMAES, PSO
- optimization
- multi-objective-optimization
- nsga2
- nsga3
- genetic-algorithm
- differential-evolution
- +2 more
+149 stars
from 2,840 · score 5.01
18.josdejong / mathjs
An extensive math library for JavaScript and Node.js
- math
- javascript
- complex-numbers
- matrices
- units
- bignumbers
- +1 more
+133 stars
from 14,971 · score 4.90
19.NVIDIAGameWorks / kaolin
A PyTorch Library for Accelerating 3D Deep Learning Research
- pytorch
- 3d-deep-learning
- neural-networks
- differentiable-rendering
- artificial-intelligence
- camera-api
- +7 more
+125 stars
from 5,066 · score 4.84
20.google-deepmind / optax
Optax is a gradient processing and optimization library for JAX.
+119 stars
from 2,244 · score 4.79
21.apache / incubator-kie
Apache KIE (Knowledge Is Everything) is the home of Drools, OptaPlanner, jBPM, and Kogito.
- rule-engine
- java
- dmn
- hacktoberfest
- apache
- drools
- +3 more
+118 stars
from 6,224 · score 4.78
22.aqlaboratory / openfold
Trainable, memory-efficient, and GPU-friendly PyTorch reproduction of AlphaFold 2
- pytorch
- protein-structure
- alphafold2
+114 stars
from 3,338 · score 4.74
23.deeplearning4j / deeplearning4j
Suite of tools for deploying and training deep learning models using the JVM. Highlights include model import for keras, tensorflow, and onnx/pytorch, a modular and tiny c++ library for running math code and a java based math library on top of the core c++ library. Also includes samediff: a pytorch/tensorflow like library for running deep learn...
- java
- gpu
- deeplearning
- neural-nets
- deeplearning4j
- dl4j
- +9 more
+110 stars
from 14,164 · score 4.71
24.ashvardanian / NumKong
SIMD-accelerated distances, dot products, matrix ops, geospatial & geometric kernels for 16 numeric types — from 6-bit floats to 64-bit complex — across x86, Arm, RISC-V, and WASM, with bindings for Python, Rust, C, C++, Swift, JS, and Go 📐
+106 stars
from 1,799 · score 4.67
25.google / s2geometry
Computational geometry and spatial indexing on the sphere
- geometry
- spherical-geometry
- s2
- spatial-indexing
+102 stars
from 2,645 · score 4.63
26.pydata / xarray
N-D labeled arrays and datasets in Python
+101 stars
from 4,119 · score 4.62
27.chaidiscovery / chai-lab
Chai-1, SOTA model for biomolecular structure prediction
+87 stars
from 1,921 · score 4.48
28.evo-design / evo
Biological foundation modeling from molecular to genome scale
+86 stars
from 1,501 · score 4.47
29.runmat-org / runmat
Open source math and physics engine that executes MATLAB-syntax code. Features a modern compiler, automatic GPU acceleration for large calculations, and support for math on geometry / FEA calculations.
- matlab
- rust
- jit-compiler
- linear-algebra
- mathematics
- numerical-analysis
- +6 more
+64 stars
from 207 · score 4.17
30.simbody / simbody
High-performance C++ multibody dynamics/physics library for simulating articulated biomechanical and mechanical systems like vehicles, robots, and the human skeleton.
- multibody-dynamics
- physics-engine
- physics-simulation
- robotics
- biomechanics
+62 stars
from 2,507 · score 4.14
31.mlange-42 / ark
Ark -- Archetype-based Entity Component System (ECS) for Go.
- ecs
- entity-component-system
- go
- golang
- agent-based-modeling
- gamedev
- +2 more
+54 stars
from 251 · score 4.01
32.prov-gigapath / prov-gigapath
Prov-GigaPath: A whole-slide foundation model for digital pathology from real-world data
+48 stars
from 597 · score 3.89
33.jerryji1993 / DNABERT
DNABERT: pre-trained Bidirectional Encoder Representations from Transformers model for DNA-language in genome
- kmer
- dnabert-model
- kmer-format
- gpu
- sequence
- genome
- +4 more
+41 stars
from 742 · score 3.74
34.MAGICS-LAB / DNABERT_2
[ICLR 2024] DNABERT-2: Efficient Foundation Model and Benchmark for Multi-Species Genome
- dataset
- dna
- dna-processing
- dna-training
- genome
- genome-analysis
- +10 more
+38 stars
from 481 · score 3.66
35.aurora-opensource / au
A C++14-compatible physical units library with no dependencies and a single-file delivery option. Emphasis on safety, accessibility, performance, and developer experience.
- cpp
- cpp14
- cpp14-library
- dimensional-analysis
- physical-quantities
- quantity
- +11 more
+31 stars
from 418 · score 3.47
36.calico / borzoi
RNA-seq prediction with deep convolutional neural networks.
+31 stars
from 238 · score 3.47
37.mdolab / OpenAeroStruct
OpenAeroStruct is a lightweight tool that performs aerostructural optimization using OpenMDAO.
- openmdao
- optimization
- aerodynamics
- open-source
+29 stars
from 259 · score 3.40
38.biomap-research / scFoundation
The repository host gives no description.
+28 stars
from 404 · score 3.37
+27 stars
from 1,827 · score 3.33
40.DLR-SC / tigl
The TiGL Geometry Library to process aircraft geometries in pre-design.
- opencascade
- aircraft
- c-plus-plus
- geometry
- b-spline
- cpacs
- +1 more
+26 stars
from 284 · score 3.30
41.HazyResearch / hyena-dna
Official implementation for HyenaDNA, a long-range genomic foundation model built with Hyena
- foundation-models
- genomics
- language-models
+25 stars
from 781 · score 3.26
42.datamol-io / datamol
Molecular Processing Made Easy.
- python
- molecule
- rdkit
- drug-discovery
- drug-design
- molecules
- +2 more
+25 stars
from 531 · score 3.26
43.epam / Indigo
Universal cheminformatics toolkit, utilities and database search tools
- indigo
- bingo
- cheminformatics
- chemistry
- python
- dotnet
- +9 more
+25 stars
from 389 · score 3.26
44.rigetti / pyquil
A Python library for quantum programming using Quil.
- forest
- quil
- quantum-computing
- quantum-programming
+21 stars
from 1,479 · score 3.09
45.kuleshov-group / caduceus
Bi-Directional Equivariant Long-Range DNA Sequence Modeling
+21 stars
from 232 · score 3.09
46.bigdatagenomics / adam
ADAM is a genomics analysis platform with specialized file formats built using Apache Avro, Apache Spark, and Apache Parquet. Apache 2 licensed.
- spark
- big-data
- bioinformatics
- genomics
- parquet
- avro
- +4 more
+16 stars
from 1,043 · score 2.83
47.Perturbation-Response-Prediction / PRnet
PRnet is a flexible and scalable perturbation-conditioned generative model predicting transcriptional responses to unseen complex perturbations at bulk and single-cell levels.
+14 stars
from 78 · score 2.71
48.AstraZeneca / chemicalx
A PyTorch and TorchDrug based deep learning library for drug pair scoring. (KDD 2022)
- deep-learning
- pytorch
- deep-chemistry
- graph-neural-network
- drug
- drug-pair
- +13 more
+13 stars
from 775 · score 2.64
49.fastlib / fCWT
The fast Continuous Wavelet Transform (fCWT) is a library for fast calculation of CWT.
- cwt
- matlab
- cpp
- optimization
- c
- fast
- +3 more
+13 stars
from 391 · score 2.64
50.thi-ng / geom
2D/3D geometry toolkit for Clojure/Clojurescript
- geometry
- visualization
- mesh-generation
- opengl
- webgl
- voxel
- +6 more
+12 stars
from 986 · score 2.56
51.ImagingDataCommons / slim
Interoperable web-based DICOM slide microscopy viewer and annotation tool
+12 stars
from 161 · score 2.56
52.gistrec / geo-utils-cpp
Tiny header-only C++17 library for lat/lng geometry: distance, bearing, area, point-in-polygon and path proximity
- cpp
- geometry
- geospatial
- gis
- gps
- haversine
- +9 more
+12 stars
from 43 · score 2.56
+11 stars
from 618 · score 2.48
54.calico / basenji
Sequential regulatory activity predictions with deep convolutional neural networks.
+11 stars
from 467 · score 2.48
55.blueqat / blueqatSDK
Quantum Computer Library for Everyone
- quantum
- python
- quantum-computing
- quantum-algorithms
- quantum-programming-language
- quantum-computer-simulator
- +1 more
+11 stars
from 379 · score 2.48
56.google / makaniArchived
Makani was a project to develop a commercial-scale airborne wind turbine, culminating in a flight test of the Makani M600 off the coast of Norway. All Makani software has now been open-sourced. This repository contains the working Makani flight simulator, controller (autopilot), visualizer, and command center flight monitoring tools. Additionally, almost all avionics firmware is also included, albeit potentially not in a buildable state, due to the removal of some third-party proprietary code. We hope that this code will be inspirational and useful to the kite-based windpower and wider communities.
- makani
- wind
- renewable-energy
- energy-kites
- wind-power
+10 stars
from 1,193 · score 2.40
57.awslabs / dgl-lifesci
Python package for graph neural networks in chemistry and biology
- deep-learning
- graph-neural-networks
- dgl
- cheminformatics
- bioinformatics
- geometric-deep-learning
- +2 more
+10 stars
from 801 · score 2.40
58.lemire / fastmod
A C/C++ header file for fast 32-bit division remainders (and divisibility tests) on 64-bit hardware.
- performance
+10 stars
from 345 · score 2.40
59.dockstring / dockstring
A Python package for molecular docking with an extensive, highly-curated dataset and a set of realistic benchmark tasks for drug discovery.
+9 stars
from 184 · score 2.30
60.MolecularAI / ReinventArchived
The repository host gives no description.
- cheminformatics
- neural-networks
- astrazeneca
- reinforcement-learning
- denovo-design
- transfer-learning
+7 stars
from 371 · score 2.08
61.davidmoten / rtree
Immutable in-memory R-tree and R*-tree implementations in Java with reactive api
+6 stars
from 1,138 · score 1.95
62.lifanchen-simm / transformerCPI
TransformerCPI: Improving compound–protein interaction prediction by sequence-based deep learning with self-attention mechanism and label reversal experiments(BIOINFORMATICS 2020) https://doi.org/10.1093/bioinformatics/btaa524
- self-attention
- compound-protein-interaction
- transformercpi
- structure-free-virtual-sreening
- drug-target-identification
- drug-discovery
+5 stars
from 154 · score 1.79
+5 stars
from 106 · score 1.79
64.adalca / neurite
Neural networks toolbox focused on medical image analysis
- python
- keras
- convolutional-neural-networks
- brain
- medical-imaging
- medical-image-computing
- +1 more
+4 stars
from 373 · score 1.61
65.jhomlala / feather
Flutter weather application with beautiful UI and UX.
+3 stars
from 688 · score 1.39
+3 stars
from 476 · score 1.39
67.DICOMcloud / DICOMcloud
Azure friendly DICOMweb part 18 .NET server with qido-rs, wado-rs, stow-rs, wado-uri RESTful implementation
- dicom
- dicomweb
- dicomcloud
- wado
- wado-uri
- wado-rs
- +5 more
+3 stars
from 232 · score 1.39
68.MengeCrowdSim / Menge
The source code for the Menge crowd simulation framework
+3 stars
from 152 · score 1.39
69.MinesJTK / jtk
The Mines Java Toolkit
- geophysics
- scientific-computing
- visualization
- mines-java-toolkit
- java
- signal-processing
+3 stars
from 85 · score 1.39
+3 stars
from 83 · score 1.39
71.mrantonSG / nova_DSO_tracker
Nova DSO Tracker is an open-source Flask application for astrophotographers, providing real-time tracking of deep-sky objects' altitude, observability prediction, and integration with Stellarium and SIMBAD databases.
+3 stars
from 20 · score 1.39
72.unmirihealth / unmiri-ngs-fhir-schema
Vendor-agnostic, FHIR-Genomics-aligned API contract for cross-vendor NGS interpretation. JSON Schema + TypeScript + Python pydantic.
+3 stars
from 2 · score 1.39
73.GPflow / GPflowOpt
Bayesian Optimization using GPflow
- gpflow
- bayesian-optimization
- machine-learning
- hyperparameter-optimization
+2 stars
from 274 · score 1.10
74.tenro-ai / tenro-python
Open-source simulation harness for testing AI agents. Simulate LLM and tool calls to test edge cases, failure paths, and agent logic without live API calls.
- ai-agents
- ai-testing
- llm
- llm-evaluation
- prompt-testing
- pytest
- +4 more
+2 stars
from 5 · score 1.10
75.MKL-NET / MKL.NET
A simple cross platform .NET API for Intel MKL
- mkl
- cross-platform
- matrix
- linear-algebra
- differentiation
- integration
- +4 more
+1 stars
from 181 · score 0.69