1.ntfargo / Relapse-Exploit
Exploit chain for PS5 7.00 - 13.60
+929 stars
from 1,718 · score 6.84
Trending repositories
Ranked by Attention Score: stars gained over the last 30 complete days
1–100 of 126 by Attention Score · Oct 5, 2026 – Nov 3, 2026 (UTC)
+412 stars
from 28,631 · score 6.02
3.heise3 / ExtremaRank
Native R and Python sample-deletion robustness for omics: candidate certificates, minimum deletion bounds, Bioconductor model refits and donor-level pseudobulk
- bioinformatics
- exact-optimization
- metabolomics
- paired-data
- proteomics
- python
- +14 more
+288 stars
from 1 · score 5.67
4.WenyuChiou / ai-research-skills
Universal SKILL.md catalog for research workflows: literature review, research design, project memory, manuscript writing, and cross-agent delegation for Claude Code, Codex, Gemini, Cursor, OpenClaw, and generic AI clients.
- academic-writing
- ai-skills
- notebooklm
- obsidian
- zotero
- claude-code
- +14 more
+279 stars
from 300 · score 5.63
5.PavelDoGreat / WebGL-Fluid-Simulation
Play with fluids in your browser (works even on mobile)
- fluid
- webgl
- simulation
- gpu
- navier-stokes
+120 stars
from 16,678 · score 4.80
6.deepchem / deepchem
Democratizing Deep-Learning for Drug Discovery, Quantum Chemistry, Materials Science and Biology
- drug-discovery
- quantum-chemistry
- deep-learning
- biology
- materials-science
- hacktoberfest
+96 stars
from 7,027 · score 4.57
7.boyter / scc
Sloc, Cloc and Code: scc is a very fast accurate code counter with complexity calculations and COCOMO estimates written in pure Go
+66 stars
from 8,791 · score 4.20
8.jwohlwend / boltz
Official repository for the Boltz biomolecular interaction models
- binding-prediction
- drug-discovery
- protein-structure
+59 stars
from 4,230 · score 4.09
9.pyvista / pyvista
3D visualization and mesh analysis for science and engineering
- vtk
- python
- visualization
- 3d
- meshviewer
- scientific-visualization
- +6 more
+48 stars
from 3,827 · score 3.89
+44 stars
from 12,346 · score 3.81
11.OHIF / Viewers
OHIF zero-footprint DICOM viewer and oncology specific Lesion Tracker, plus shared extension packages
- nci-itcr
- nci-qin
- quantitative-imaging
- imaging-informatics
- cancer-imaging-research
- dicom
- +10 more
+38 stars
from 4,358 · score 3.66
+35 stars
from 3,609 · score 3.58
+35 stars
from 1,863 · score 3.58
14.Turfjs / turf
A modular geospatial engine written in JavaScript and TypeScript
- javascript
- algorithm
- computational-geometry
- geojson
- turf
- gis
- +3 more
+27 stars
from 10,504 · score 3.33
15.mikedh / trimesh
Python library for loading and using triangular meshes.
- mesh
- triangular-meshes
- geometry
- python
+24 stars
from 3,691 · score 3.22
16.gcorso / DiffDock
Implementation of DiffDock: Diffusion Steps, Twists, and Turns for Molecular Docking
- diffusion-models
- docking
- binding
- computational-biology
- equivariance
- machine-learning
- +2 more
+23 stars
from 1,576 · score 3.18
+22 stars
from 2,259 · score 3.14
18.bayesian-optimization / BayesianOptimization
A Python implementation of global optimization with gaussian processes.
- optimization
- gaussian-processes
- bayesian-optimization
- python
- simple
+19 stars
from 8,710 · score 3.00
+19 stars
from 2,818 · score 3.00
+19 stars
from 1,644 · score 3.00
21.aidenybai / million
Optimizing compiler for React
- hacktoberfest
- million
- millionjs
- virtual-dom
- react
- blockdom
- +11 more
+15 stars
from 17,648 · score 2.77
22.zarr-developers / zarr-python
An implementation of chunked, compressed, N-dimensional arrays for Python.
- zarr
- ndimensional-arrays
- compressed
- python
+15 stars
from 2,065 · score 2.77
23.pathsim / pathsim
A Python native dynamical system simulation framework in the block diagram paradigm.
- blockdiagram
- control-systems
- hierarchical-modeling
- nonlinear-dynamics
- simulation
- system-simulation
- +14 more
+15 stars
from 497 · score 2.77
24.HIPS / autograd
Efficiently computes derivatives of NumPy code.
- autograd
- automatic-differentiation
- numpy
- python
- deep-learning
- derivative
- +8 more
+14 stars
from 7,537 · score 2.71
25.MFlowCode / MFC
Exascale multiphase flow solver — 2025 Gordon Bell Prize Finalist | 200T grid points on 43K+ GPUs
+14 stars
from 425 · score 2.71
26.paulmillr / noble-post-quantum
Auditable & minimal JS implementation of public-key post-quantum cryptography
- dilithium
- kyber
- ml-kem
- post-quantum-cryptography
- sphincs
- sphincs-plus
- +14 more
+14 stars
from 356 · score 2.71
27.PythonOT / POT
POT : Python Optimal Transport
- optimal-transport
- numerical-optimization
- machine-learning
- emd
- ot-mapping-estimation
- wasserstein-barycenter
- +10 more
+13 stars
from 2,847 · score 2.64
28.RosettaCommons / RoseTTAFold
This package contains deep learning models and related scripts for RoseTTAFold
+13 stars
from 2,267 · score 2.64
29.guofei9987 / scikit-opt
Genetic Algorithm, Particle Swarm Optimization, Simulated Annealing, Ant Colony Optimization Algorithm,Immune Algorithm, Artificial Fish Swarm Algorithm, Differential Evolution and TSP(Traveling salesman)
- genetic-algorithm
- pso
- particle-swarm-optimization
- tsp
- travelling-salesman-problem
- simulated-annealing
- +7 more
+12 stars
from 6,714 · score 2.56
30.microsoft / DirectXMath
DirectXMath is an all inline SIMD C++ linear algebra library for use in games and graphics apps
+12 stars
from 1,804 · score 2.56
31.deepmodeling / Uni-Mol
Official Repository for the Uni-Mol Series Methods
- molecular-modeling
- pre-trained-model
- pretraining
- deep-learning
+12 stars
from 1,164 · score 2.56
32.zoharbabin / web-researcher-mcp
Search the web and primary sources, read full pages, and check every citation. MCP server for Claude, Cursor, Codex and more. Runs on your machine.
+12 stars
from 64 · score 2.56
33.ikpil / Box2D.NET
Box2D.NET - a C# port of Box2D, is a 2D physics engine for games, .NET, Unity3D, servers
- 2d
- 2d-game
- box2d
- csharp
- game
- game-development
- +8 more
+10 stars
from 216 · score 2.40
34.facebookresearch / esmArchived
Evolutionary Scale Modeling (esm): Pretrained language models for proteins
+9 stars
from 4,166 · score 2.30
35.suyashkumar / dicom
⚡High Performance DICOM Medical Image Parser in Go.
- dicom
- dicom-images
- golang
- golang-library
- golang-package
- parser
- +10 more
+9 stars
from 1,087 · score 2.30
36.mims-harvard / PrimeKG
Precision Medicine Knowledge Graph (PrimeKG)
- knowledge-graph
- precision-medicine
- therapeutics
- bioinformatics
- dataset
- graph-machine-learning
- +2 more
+9 stars
from 829 · score 2.30
37.OATML-Markslab / ProteinGym
Official repository for the ProteinGym benchmarks
- benchmark
- computational-biology
- protein
- protein-design
- protein-fitness
+9 stars
from 475 · score 2.30
38.dpilger26 / NumCpp
C++ implementation of the Python Numpy library
- python
- numpy
- c-plus-plus
- numerical-analysis
- scientific-computing
- algorithms
- +3 more
+8 stars
from 3,961 · score 2.20
39.PyWavelets / pywt
PyWavelets - Wavelet Transforms in Python
- wavelets
- wavelet-transform
- signal-processing
- image-processing
- continuous-wavelet
+8 stars
from 2,404 · score 2.20
+7 stars
from 3,767 · score 2.08
41.markrogoyski / math-php
Powerful modern math library for PHP: Features descriptive statistics and regressions; Continuous and discrete probability distributions; Linear algebra with matrices and vectors, Numerical analysis; special mathematical functions; Algebra
- math
- mathematics
- linear-algebra
- statistics
- matrix
- probability
- +11 more
+7 stars
from 2,408 · score 2.08
42.DavidArayan / ezy-slice
An open source mesh slicer framework for Unity3D Game Engine. Written in C#.
+7 stars
from 2,274 · score 2.08
43.DTolm / VkFFT
Vulkan/CUDA/HIP/OpenCL/Level Zero/Metal Fast Fourier Transform library
+7 stars
from 1,780 · score 2.08
44.molecularsets / moses
Molecular Sets (MOSES): A Benchmarking Platform for Molecular Generation Models
- machine-learning
- generative-models
- drug-discovery
- benchmark
+7 stars
from 990 · score 2.08
45.vqdang / hover_net
Simultaneous Nuclear Instance Segmentation and Classification in H&E Histology Images.
+7 stars
from 749 · score 2.08
46.chainer / chainer-chemistry
Chainer Chemistry: A Library for Deep Learning in Biology and Chemistry
- deep-learning
- chemistry
- neural-network
- biology
- chainer
- python
- +1 more
+7 stars
from 708 · score 2.08
47.TUDelft-CNS-ATM / bluesky
The open source air traffic simulator
- python
- traffic
- aircraft
- simulation
- air-traffic-control
- air-transport
- +11 more
+7 stars
from 568 · score 2.08
48.kreshuklab / panseg
A tool for cell instance aware segmentation in densely packed 3D volumetric images
- segmentation
- deep-learning
- bioinformatics
- neural-network
- bioimage-analysis
- image-segmentation
- +1 more
+7 stars
from 130 · score 2.08
49.Aceinna / gnss-ins-sim
Open-source GNSS + inertial navigation, sensor fusion simulator. Motion trajectory generator, sensor models, and navigation
- inertial-navigation-systems
- gnss
- gps
- imu
- integrated-navigation
+6 stars
from 1,492 · score 1.95
50.Mariewelt / OpenChem
OpenChem: Deep Learning toolkit for Computational Chemistry and Drug Design Research
- computational-chemistry
- computational-biology
- deep-learning
- deep-neural-networks
- graph-convolutional-networks
- drug-discovery
- +5 more
+6 stars
from 753 · score 1.95
51.ElliotXie / autozyme
Autonomous multi-agent framework to optimize scientific software
- acceleration
- agentic-ai
- ai-agents
- bioinformatics
- code-optimization
- genomics
- +11 more
+6 stars
from 51 · score 1.95
52.MikeMcl / bignumber.js
A JavaScript library for arbitrary-precision decimal and non-decimal arithmetic
- bignumber
- javascript
- arbitrary-precision
- decimal-places
- bigdecimal
+5 stars
from 7,008 · score 1.79
53.marcomusy / vedo
A python module for scientific analysis of 3D data based on VTK and Numpy
- 3d-graphics
- vtk
- 3d
- mesh
- simulations
- scientific-visualization
- +5 more
+5 stars
from 2,270 · score 1.79
54.brick / math
Arbitrary-precision arithmetic library for PHP
- php
- arbitrary-precision
- biginteger
- bigdecimal
- bigrational
- gmp
- +1 more
+5 stars
from 2,175 · score 1.79
55.autodiff / autodiff
automatic differentiation made easier for C++
- automatic-differentiation
- auto-differentiation
- autodiff
- autodifferentiation
- differentiation
- derivatives
- +1 more
+5 stars
from 1,958 · score 1.79
56.ljvmiranda921 / pyswarms
A research toolkit for particle swarm optimization in Python
- particle-swarm-optimization
- optimization-tools
- pso
- global-optimization
- swarm-intelligence
- machine-learning
- +5 more
+5 stars
from 1,396 · score 1.79
57.softwareQinc / qpp
Modern C++ quantum computing library
- quantum-computing
- c-plus-plus
- cpp
- cpp11
- quantum
- simulator
- +2 more
+5 stars
from 673 · score 1.79
58.pydata / numexpr
Fast numerical array expression evaluator for Python, NumPy, Pandas, PyTables and more
+4 stars
from 2,541 · score 1.61
59.giacomelli / GeneticSharp
GeneticSharp is a fast, extensible, multi-platform and multithreading C# Genetic Algorithm library that simplifies the development of applications using Genetic Algorithms (GAs).
- genetic-algorithms
- artificial-intelligence
- c-sharp
- dotnet
- dotnet-core
- dotnet-standard
- +3 more
+4 stars
from 1,372 · score 1.61
60.msteinbeck / tinyspline
ANSI C library for NURBS, B-Splines, and Bézier curves with interfaces for C++, C#, D, Go, Java, Javascript, Lua, Octave, PHP, Python, R, and Ruby.
- nurbs
- b-splines
- bezier-curves
- splines
+4 stars
from 1,354 · score 1.61
61.owlbarn / owl
Owl - OCaml Scientific Computing @ https://ocaml.xyz
- matrix
- linear-algebra
- ndarray
- statistical-functions
- topic-modeling
- regression
- +14 more
+4 stars
from 1,354 · score 1.61
62.MaxHalford / eaopt
:four_leaf_clover: Evolutionary optimization library for Go (genetic algorithm, partical swarm optimization, differential evolution)
- go
- optimization
- parallel
- machine-learning
- genetic-algorithm
- speciation
- +5 more
+4 stars
from 903 · score 1.61
63.microsoft / evodiff
Generation of protein sequences and evolutionary alignments via discrete diffusion models
- discrete-diffusion
- generative-model
- multiple-sequence-alignment
- protein-sequences
+4 stars
from 686 · score 1.61
64.Martinsos / edlib
Lightweight, super fast C/C++ (& Python) library for sequence alignment using edit (Levenshtein) distance.
- sequence-alignment
- edit-distance
- levehnstein-distance
- library
- c-plus-plus
- alignment-path
- +2 more
+4 stars
from 608 · score 1.61
65.gao-lab / GLUE
Graph-linked unified embedding for single-cell multi-omics data integration
- bioinformatics
- deep-learning
- single-cell
- single-cell-multiomics
+4 stars
from 480 · score 1.61
66.shenwei356 / taxonkit
A Practical and Efficient NCBI Taxonomy Toolkit, also supports creating NCBI-style taxdump files for custom taxonomies like GTDB/ICTV
- bioinformatics
- taxonomy
- cross-platform
- lineage
- lca
- taxid
- +2 more
+4 stars
from 480 · score 1.61
67.songlab-cal / gpn
Genomic Pretrained Network - GPN, GPN-MSA, PhyloGPN, GPN-Star
- dna
- language-model
- variant-effect-prediction
- genomics
+4 stars
from 383 · score 1.61
68.erayzesen / QuarkPhysics
A 2D Soft Body and Rigid Body Physics Engine.
- 2d-physics-engine
- game-development
- physics-engine
- rigid-bodies
- soft-bodies
- physics-simulation
+4 stars
from 296 · score 1.61
69.MLT-OSS / FirstData
The World's Most Comprehensive, Authoritative, and Structured Open Source Data Source Knowledge Base
- mcp
- data-sources
- ai
- awesome-list
- datasets
- fact-checking
- +14 more
+4 stars
from 182 · score 1.61
70.sustainable-processes / summit
Optimising chemical reactions using machine learning
- chemistry
- machine-learning
- optimization
- bayesian-optimization
- neural-networks
- drug-discovery
- +4 more
+4 stars
from 151 · score 1.61
71.spatie / laravel-analytics
A Laravel package to retrieve pageviews and other data from Google Analytics
- laravel
- php
- analytics
- statistics
+3 stars
from 3,241 · score 1.39
72.Habrador / Computational-geometry
Computational Geometry Unity library with implementations of intersection algorithms, triangulations like delaunay, voronoi diagrams, polygon clipping, bezier curves, ear clipping, convex hulls, mesh simplification, etc
- unity3d
- computational-geometry
- voronoi
- intersections
- convex-hull
- polygon-clipping
- +14 more
+3 stars
from 1,469 · score 1.39
73.hail-is / hail
Cloud-native genomic dataframes and batch computing
- genetics
- vcf
- genomics
- gwas
- bioinformatics
- python
- +2 more
+3 stars
from 1,079 · score 1.39
74.ddemidov / amgcl
C++ library for solving large sparse linear systems with algebraic multigrid method
- amg
- c-plus-plus
- sparse-linear-systems
- opencl
- cuda
- gpgpu
- +6 more
+3 stars
from 882 · score 1.39
+3 stars
from 735 · score 1.39
76.vcflib / vcflib
C++ library and cmdline tools for parsing and manipulating VCF files with python and zig bindings
- variant-calling
- genomics
- vcf-manipulation
- genotyping
- haplotypecaller
+3 stars
from 686 · score 1.39
+3 stars
from 534 · score 1.39
78.fbcosentino / godot-simplified-flightsim
Simplified Flight Simulation library (addon) for Godot Engine
+3 stars
from 307 · score 1.39
79.peterstace / simplefeatures
Simple Features is a pure Go Implementation of the OpenGIS Simple Feature Access Specification
+3 stars
from 172 · score 1.39
80.vlang / vtl
The V Tensor Library
- v
- hacktoberfest
- autograd
- deep-learning
- linear-algebra
- machine-learning
- +5 more
+3 stars
from 169 · score 1.39
81.clean-css / clean-css
Fast and efficient CSS optimizer for node.js and the Web
- css
- minification
- optimization
- css-optimizations
- css-optimizer
- clean-css
+2 stars
from 4,197 · score 1.10
82.romeric / Fastor
A lightweight high performance tensor algebra framework for modern C++
+2 stars
from 843 · score 1.10
+2 stars
from 816 · score 1.10
84.aeturrell / skimpy
skimpy is a light weight tool that provides summary statistics about variables in data frames within the console.
- eda
- pandas
- data-science
- exploratory-data-analysis
- summary-statistics
- statistics
+2 stars
from 516 · score 1.10
85.seyonechithrananda / bert-loves-chemistry
bert-loves-chemistry: a repository of HuggingFace models applied on chemical SMILES data for drug design, chemical modelling, etc.
- huggingface
- bert
- chemical-modelling
- chemical-smiles-data
+2 stars
from 501 · score 1.10
86.maximtrp / scikit-posthocs
Multiple Pairwise Comparisons (Post Hoc) Tests in Python
- posthoc-comparisons
- posthoc-tests
- python
- scikit
- statistical-analysis
- statistics
- +1 more
+2 stars
from 389 · score 1.10
87.DmitriBogdanov / UTL
Collection of self-contained header-only libraries for C++17
+2 stars
from 335 · score 1.10
88.ECSIM / opem
OPEM (Open Source PEM Fuel Cell Simulation Tool)
- chemistry
- pem
- fuel-cell
- opem
- script
- python
- +8 more
+2 stars
from 232 · score 1.10
89.mojaie / MolecularGraph.jl
Graph-based molecule modeling toolkit for cheminformatics
- cheminformatics
- molecular-modeling
- chemistry
- toolkit
- julia
- julia-language
- +3 more
+2 stars
from 229 · score 1.10
90.mcs07 / MolVS
Molecule Validation and Standardization
- rdkit
- python
- chemistry
- cheminformatics
- standardization
- validation
+2 stars
from 187 · score 1.10
91.theislab / chemCPA
Code for "Predicting Cellular Responses to Novel Drug Perturbations at a Single-Cell Resolution", NeurIPS 2022.
- disentanglement
- drug-discovery
- genomics
- perturbation
- single-cell
- transfer-learning
+2 stars
from 160 · score 1.10
92.jimmyorourke / plotlypp
Plotly for C++. A C++ interface to the Plotly.js figure spec, for creating interactive data visualizations.
- charts
- cpp
- graphs
- plotly
- plotting
- visualization
- +4 more
+2 stars
from 146 · score 1.10
93.ElliotXie / CASSIA
CASSIA: A Multi-Agent LLM-Based Single-Cell Cell Type Annotation Framework
- ai4science
- llm
- multiagent-systems
- prompt-engineering
- retrieved-augmented-generation
- singlecell
- +7 more
+2 stars
from 107 · score 1.10
94.Necrom4 / calcium.nvim
Neovim plugin to calculate mathematical expressions within a buffer with visual mode, functions and variable support.
- calculator
- lua
- math
- neovim
- neovim-plugin
+2 stars
from 68 · score 1.10
95.chrieke / geojson-invalid-geometry
🗺️ List of GeoJSON invalid geometry issues with example files
+2 stars
from 50 · score 1.10
96.emptymalei / statisticalphysics
open source E-book on statistical physics
- statistical-physics
- statistical-mechanics
+2 stars
from 50 · score 1.10
97.pmp-library / pmp-library
The Polygon Mesh Processing Library
- mesh-processing
- geometry-processing
- polygon-mesh
- triangle-mesh
- c-plus-plus
- surface-mesh
- +9 more
+1 stars
from 1,509 · score 0.69
+1 stars
from 1,245 · score 0.69
99.kzampog / cilantro
A lean C++ library for working with point cloud data
- point-cloud
- icp
- ransac
- convex-hull
- 3d-visualization
- k-means
- +14 more
+1 stars
from 1,138 · score 0.69
100.bcbio / bcbio-nextgen
Validated, scalable, community developed variant calling, RNA-seq and small RNA analysis
+1 stars
from 1,029 · score 0.69