+3,195 stars
from 25,848 · score 8.07
Trending repositories
Ranked by Attention Score: stars gained over the last 180 complete days
1–100 of 149 by Attention Score · May 8, 2026 – Nov 3, 2026 (UTC)
+1,510 stars
from 10,880 · score 7.32
3.PavelDoGreat / WebGL-Fluid-Simulation
Play with fluids in your browser (works even on mobile)
- fluid
- webgl
- simulation
- gpu
- navier-stokes
+567 stars
from 16,231 · score 6.34
4.boyter / scc
Sloc, Cloc and Code: scc is a very fast accurate code counter with complexity calculations and COCOMO estimates written in pure Go
+539 stars
from 8,318 · score 6.29
5.WenyuChiou / ai-research-skills
Universal SKILL.md catalog for research workflows: literature review, research design, project memory, manuscript writing, and cross-agent delegation for Claude Code, Codex, Gemini, Cursor, OpenClaw, and generic AI clients.
- academic-writing
- ai-skills
- notebooklm
- obsidian
- zotero
- claude-code
- +14 more
+523 stars
from 56 · score 6.26
6.deepchem / deepchem
Democratizing Deep-Learning for Drug Discovery, Quantum Chemistry, Materials Science and Biology
- drug-discovery
- quantum-chemistry
- deep-learning
- biology
- materials-science
- hacktoberfest
+450 stars
from 6,673 · score 6.11
7.jwohlwend / boltz
Official repository for the Boltz biomolecular interaction models
- binding-prediction
- drug-discovery
- protein-structure
+373 stars
from 3,916 · score 5.92
8.mtahiraslan / data-analyst-roadmap
Based on my own experience, I believe this roadmap provides clear answers to all the key questions about becoming a data analyst from scratch, including which technologies and programming languages to learn, what soft skills are essential, and how to start a professional career in this field.
- blogs
- businessintelligence
- courses
- data
- dataanalysis
- dataanalyst
- +14 more
+334 stars
from 788 · score 5.81
9.OHIF / Viewers
OHIF zero-footprint DICOM viewer and oncology specific Lesion Tracker, plus shared extension packages
- nci-itcr
- nci-qin
- quantitative-imaging
- imaging-informatics
- cancer-imaging-research
- dicom
- +10 more
+262 stars
from 4,134 · score 5.57
10.pyvista / pyvista
3D visualization and mesh analysis for science and engineering
- vtk
- python
- visualization
- 3d
- meshviewer
- scientific-visualization
- +6 more
+257 stars
from 3,618 · score 5.55
11.guofei9987 / scikit-opt
Genetic Algorithm, Particle Swarm Optimization, Simulated Annealing, Ant Colony Optimization Algorithm,Immune Algorithm, Artificial Fish Swarm Algorithm, Differential Evolution and TSP(Traveling salesman)
- genetic-algorithm
- pso
- particle-swarm-optimization
- tsp
- travelling-salesman-problem
- simulated-annealing
- +7 more
+233 stars
from 6,493 · score 5.46
12.aidenybai / million
Optimizing compiler for React
- hacktoberfest
- million
- millionjs
- virtual-dom
- react
- blockdom
- +11 more
+227 stars
from 17,436 · score 5.43
13.Turfjs / turf
A modular geospatial engine written in JavaScript and TypeScript
- javascript
- algorithm
- computational-geometry
- geojson
- turf
- gis
- +3 more
+208 stars
from 10,323 · score 5.34
+192 stars
from 1,706 · score 5.26
15.appsinacup / godot-rapier-physics
Godot Rapier Physics – 2D and 3D physics engine for the Godot game engine. with better stability, performance, liquids, determinism, state serialization and no ghost collisions.
- godot
- godot-engine
- godot4
- godotengine
- rapier
- 2d
- +3 more
+178 stars
from 860 · score 5.19
16.mikedh / trimesh
Python library for loading and using triangular meshes.
- mesh
- triangular-meshes
- geometry
- python
+170 stars
from 3,545 · score 5.14
17.pathsim / pathsim
A Python native dynamical system simulation framework in the block diagram paradigm.
- blockdiagram
- control-systems
- hierarchical-modeling
- nonlinear-dynamics
- simulation
- system-simulation
- +14 more
+145 stars
from 367 · score 4.98
18.bayesian-optimization / BayesianOptimization
A Python implementation of global optimization with gaussian processes.
- optimization
- gaussian-processes
- bayesian-optimization
- python
- simple
+144 stars
from 8,585 · score 4.98
19.facebookresearch / esmArchived
Evolutionary Scale Modeling (esm): Pretrained language models for proteins
+141 stars
from 4,034 · score 4.96
20.pydata / numexpr
Fast numerical array expression evaluator for Python, NumPy, Pandas, PyTables and more
+137 stars
from 2,408 · score 4.93
+133 stars
from 3,511 · score 4.90
+124 stars
from 1,539 · score 4.83
23.zarr-developers / zarr-python
An implementation of chunked, compressed, N-dimensional arrays for Python.
- zarr
- ndimensional-arrays
- compressed
- python
+112 stars
from 1,968 · score 4.73
+104 stars
from 2,177 · score 4.65
25.gcorso / DiffDock
Implementation of DiffDock: Diffusion Steps, Twists, and Turns for Molecular Docking
- diffusion-models
- docking
- binding
- computational-biology
- equivariance
- machine-learning
- +2 more
+104 stars
from 1,495 · score 4.65
+101 stars
from 2,736 · score 4.62
27.mims-harvard / PrimeKG
Precision Medicine Knowledge Graph (PrimeKG)
- knowledge-graph
- precision-medicine
- therapeutics
- bioinformatics
- dataset
- graph-machine-learning
- +2 more
+96 stars
from 742 · score 4.57
28.MFlowCode / MFC
Exascale multiphase flow solver — 2025 Gordon Bell Prize Finalist | 200T grid points on 43K+ GPUs
+87 stars
from 352 · score 4.48
29.HIPS / autograd
Efficiently computes derivatives of NumPy code.
- autograd
- automatic-differentiation
- numpy
- python
- deep-learning
- derivative
- +8 more
+84 stars
from 7,467 · score 4.44
30.PythonOT / POT
POT : Python Optimal Transport
- optimal-transport
- numerical-optimization
- machine-learning
- emd
- ot-mapping-estimation
- wasserstein-barycenter
- +10 more
+80 stars
from 2,780 · score 4.39
31.kjkrol / goke
High-performance, zero-allocation ECS for Go. Cache-friendly data orchestrator with type-safe iterators.
- ecs
- entity-component-system
- gamedev
- go
- goalng
- geme-engine
- +2 more
+67 stars
from 27 · score 4.22
32.vincentlaucsb / csv-parser
A modern C++ CSV parser and serializer that doesn't make you choose between ease of use or performance.
- csv
- parser
- json
- tab-separated
- csv-parser
- statistics
- +5 more
+65 stars
from 1,072 · score 4.19
33.microsoft / DirectXMath
DirectXMath is an all inline SIMD C++ linear algebra library for use in games and graphics apps
+62 stars
from 1,754 · score 4.14
34.DavidArayan / ezy-slice
An open source mesh slicer framework for Unity3D Game Engine. Written in C#.
+61 stars
from 2,220 · score 4.13
+60 stars
from 3,714 · score 4.11
36.OATML-Markslab / ProteinGym
Official repository for the ProteinGym benchmarks
- benchmark
- computational-biology
- protein
- protein-design
- protein-fitness
+60 stars
from 424 · score 4.11
37.brick / math
Arbitrary-precision arithmetic library for PHP
- php
- arbitrary-precision
- biginteger
- bigdecimal
- bigrational
- gmp
- +1 more
+59 stars
from 2,121 · score 4.09
38.paulmillr / noble-post-quantum
Auditable & minimal JS implementation of public-key post-quantum cryptography
- dilithium
- kyber
- ml-kem
- post-quantum-cryptography
- sphincs
- sphincs-plus
- +14 more
+55 stars
from 315 · score 4.03
39.TUDelft-CNS-ATM / bluesky
The open source air traffic simulator
- python
- traffic
- aircraft
- simulation
- air-traffic-control
- air-transport
- +11 more
+54 stars
from 521 · score 4.01
40.PyWavelets / pywt
PyWavelets - Wavelet Transforms in Python
- wavelets
- wavelet-transform
- signal-processing
- image-processing
- continuous-wavelet
+53 stars
from 2,359 · score 3.99
41.Aceinna / gnss-ins-sim
Open-source GNSS + inertial navigation, sensor fusion simulator. Motion trajectory generator, sensor models, and navigation
- inertial-navigation-systems
- gnss
- gps
- imu
- integrated-navigation
+53 stars
from 1,445 · score 3.99
42.ikpil / Box2D.NET
Box2D.NET - a C# port of Box2D, is a 2D physics engine for games, .NET, Unity3D, servers
- 2d
- 2d-game
- box2d
- csharp
- game
- game-development
- +8 more
+50 stars
from 176 · score 3.93
43.songlab-cal / gpn
Genomic Pretrained Network - GPN, GPN-MSA, PhyloGPN, GPN-Star
- dna
- language-model
- variant-effect-prediction
- genomics
+49 stars
from 338 · score 3.91
44.DTolm / VkFFT
Vulkan/CUDA/HIP/OpenCL/Level Zero/Metal Fast Fourier Transform library
+48 stars
from 1,739 · score 3.89
45.datoviz / datoviz
⚡ Datoviz: high-performance GPU rendering for scientific data visualization
- visualization
- graphics
- data-visualization
- scientific-visualization
- gpu
- vulkan
- +6 more
+47 stars
from 777 · score 3.87
46.RosettaCommons / RoseTTAFold
This package contains deep learning models and related scripts for RoseTTAFold
+46 stars
from 2,234 · score 3.85
47.pmp-library / pmp-library
The Polygon Mesh Processing Library
- mesh-processing
- geometry-processing
- polygon-mesh
- triangle-mesh
- c-plus-plus
- surface-mesh
- +9 more
+38 stars
from 1,472 · score 3.66
48.ddemidov / amgcl
C++ library for solving large sparse linear systems with algebraic multigrid method
- amg
- c-plus-plus
- sparse-linear-systems
- opencl
- cuda
- gpgpu
- +6 more
+37 stars
from 848 · score 3.64
49.MikeMcl / bignumber.js
A JavaScript library for arbitrary-precision decimal and non-decimal arithmetic
- bignumber
- javascript
- arbitrary-precision
- decimal-places
- bigdecimal
+36 stars
from 6,977 · score 3.61
50.autodiff / autodiff
automatic differentiation made easier for C++
- automatic-differentiation
- auto-differentiation
- autodiff
- autodifferentiation
- differentiation
- derivatives
- +1 more
+36 stars
from 1,927 · score 3.61
51.dpilger26 / NumCpp
C++ implementation of the Python Numpy library
- python
- numpy
- c-plus-plus
- numerical-analysis
- scientific-computing
- algorithms
- +3 more
+34 stars
from 3,935 · score 3.56
52.marcomusy / vedo
A python module for scientific analysis of 3D data based on VTK and Numpy
- 3d-graphics
- vtk
- 3d
- mesh
- simulations
- scientific-visualization
- +5 more
+34 stars
from 2,241 · score 3.56
53.molecularsets / moses
Molecular Sets (MOSES): A Benchmarking Platform for Molecular Generation Models
- machine-learning
- generative-models
- drug-discovery
- benchmark
+34 stars
from 963 · score 3.56
54.owlbarn / owl
Owl - OCaml Scientific Computing @ https://ocaml.xyz
- matrix
- linear-algebra
- ndarray
- statistical-functions
- topic-modeling
- regression
- +14 more
+32 stars
from 1,326 · score 3.50
55.hail-is / hail
Cloud-native genomic dataframes and batch computing
- genetics
- vcf
- genomics
- gwas
- bioinformatics
- python
- +2 more
+32 stars
from 1,050 · score 3.50
56.MLT-OSS / FirstData
The World's Most Comprehensive, Authoritative, and Structured Open Source Data Source Knowledge Base
- mcp
- data-sources
- ai
- awesome-list
- datasets
- fact-checking
- +14 more
+31 stars
from 155 · score 3.47
57.msteinbeck / tinyspline
ANSI C library for NURBS, B-Splines, and Bézier curves with interfaces for C++, C#, D, Go, Java, Javascript, Lua, Octave, PHP, Python, R, and Ruby.
- nurbs
- b-splines
- bezier-curves
- splines
+30 stars
from 1,328 · score 3.43
58.fbcosentino / godot-simplified-flightsim
Simplified Flight Simulation library (addon) for Godot Engine
+27 stars
from 283 · score 3.33
59.softwareQinc / qpp
Modern C++ quantum computing library
- quantum-computing
- c-plus-plus
- cpp
- cpp11
- quantum
- simulator
- +2 more
+26 stars
from 652 · score 3.30
60.Mariewelt / OpenChem
OpenChem: Deep Learning toolkit for Computational Chemistry and Drug Design Research
- computational-chemistry
- computational-biology
- deep-learning
- deep-neural-networks
- graph-convolutional-networks
- drug-discovery
- +5 more
+24 stars
from 735 · score 3.22
61.Martinsos / edlib
Lightweight, super fast C/C++ (& Python) library for sequence alignment using edit (Levenshtein) distance.
- sequence-alignment
- edit-distance
- levehnstein-distance
- library
- c-plus-plus
- alignment-path
- +2 more
+23 stars
from 589 · score 3.18
62.chainer / chainer-chemistry
Chainer Chemistry: A Library for Deep Learning in Biology and Chemistry
- deep-learning
- chemistry
- neural-network
- biology
- chainer
- python
- +1 more
+22 stars
from 693 · score 3.14
+22 stars
from 515 · score 3.14
64.gao-lab / GLUE
Graph-linked unified embedding for single-cell multi-omics data integration
- bioinformatics
- deep-learning
- single-cell
- single-cell-multiomics
+22 stars
from 462 · score 3.14
65.marcpinet / citracer
💬 Trace citation chains for any concept across research papers and render them as an interactive graph.
- academic-research
- bibliography
- citation-graph
- cli
- grobid
- literature-review
- +5 more
+22 stars
from 17 · score 3.14
66.spatie / laravel-analytics
A Laravel package to retrieve pageviews and other data from Google Analytics
- laravel
- php
- analytics
- statistics
+21 stars
from 3,223 · score 3.09
67.Habrador / Computational-geometry
Computational Geometry Unity library with implementations of intersection algorithms, triangulations like delaunay, voronoi diagrams, polygon clipping, bezier curves, ear clipping, convex hulls, mesh simplification, etc
- unity3d
- computational-geometry
- voronoi
- intersections
- convex-hull
- polygon-clipping
- +14 more
+21 stars
from 1,451 · score 3.09
68.ljvmiranda921 / pyswarms
A research toolkit for particle swarm optimization in Python
- particle-swarm-optimization
- optimization-tools
- pso
- global-optimization
- swarm-intelligence
- machine-learning
- +5 more
+21 stars
from 1,380 · score 3.09
69.ElliotXie / CASSIA
CASSIA: A Multi-Agent LLM-Based Single-Cell Cell Type Annotation Framework
- ai4science
- llm
- multiagent-systems
- prompt-engineering
- retrieved-augmented-generation
- singlecell
- +7 more
+21 stars
from 88 · score 3.09
70.Necrom4 / calcium.nvim
Neovim plugin to calculate mathematical expressions within a buffer with visual mode, functions and variable support.
- calculator
- lua
- math
- neovim
- neovim-plugin
+21 stars
from 49 · score 3.09
71.giacomelli / GeneticSharp
GeneticSharp is a fast, extensible, multi-platform and multithreading C# Genetic Algorithm library that simplifies the development of applications using Genetic Algorithms (GAs).
- genetic-algorithms
- artificial-intelligence
- c-sharp
- dotnet
- dotnet-core
- dotnet-standard
- +3 more
+20 stars
from 1,356 · score 3.04
72.tequilahub / tequila
A High-Level Abstraction Framework for Quantum Algorithms
+20 stars
from 423 · score 3.04
73.markrogoyski / math-php
Powerful modern math library for PHP: Features descriptive statistics and regressions; Continuous and discrete probability distributions; Linear algebra with matrices and vectors, Numerical analysis; special mathematical functions; Algebra
- math
- mathematics
- linear-algebra
- statistics
- matrix
- probability
- +11 more
+19 stars
from 2,396 · score 3.00
74.Genbox / VelcroPhysics
High performance 2D collision detection system with realistic physics responses.
- physics-engine
- physics-2d
+18 stars
from 731 · score 2.94
75.bebop / poly
A Go package for engineering organisms.
- synthetic-biology
- synbio
- genetic-engineering
- molecular-biology
- bioengineering
- computational-biology
- +14 more
+17 stars
from 719 · score 2.89
76.clean-css / clean-css
Fast and efficient CSS optimizer for node.js and the Web
- css
- minification
- optimization
- css-optimizations
- css-optimizer
- clean-css
+16 stars
from 4,183 · score 2.83
77.djezzzl / database_consistency
The tool to avoid various issues due to inconsistencies and inefficiencies between a database schema and application models.
- ruby-on-rails
- activerecord
- tool
- database
- consistency
- optimization
- +3 more
+15 stars
from 1,181 · score 2.77
78.ASC-Community / AngouriMath
Open-source cross-platform symbolic algebra library for C# and F#. Can be used for both production and research purposes.
+15 stars
from 817 · score 2.77
79.shenwei356 / taxonkit
A Practical and Efficient NCBI Taxonomy Toolkit, also supports creating NCBI-style taxdump files for custom taxonomies like GTDB/ICTV
- bioinformatics
- taxonomy
- cross-platform
- lineage
- lca
- taxid
- +2 more
+15 stars
from 469 · score 2.77
80.theislab / chemCPA
Code for "Predicting Cellular Responses to Novel Drug Perturbations at a Single-Cell Resolution", NeurIPS 2022.
- disentanglement
- drug-discovery
- genomics
- perturbation
- single-cell
- transfer-learning
+15 stars
from 147 · score 2.77
81.uber-common / metta
An information security preparedness tool to do adversarial simulation.
- uber
- vagrant
- yaml
- celery
- python
- redis
- +7 more
+14 stars
from 1,134 · score 2.71
82.vcflib / vcflib
C++ library and cmdline tools for parsing and manipulating VCF files with python and zig bindings
- variant-calling
- genomics
- vcf-manipulation
- genotyping
- haplotypecaller
+14 stars
from 675 · score 2.71
83.MolSSI / cookiecutter-cms
Python-centric Cookiecutter for Molecular Computational Chemistry Packages
- cookiecutter
- python-packages
- molecular-sciences
- conda-environment
- pytest
- conda-forge
- +2 more
+14 stars
from 451 · score 2.71
84.vlang / vsl
V library to develop Artificial Intelligence and High-Performance Scientific Computations
- v
- hacktoberfest
- linear-algebra
- optimization
- sparse-systems
- computational-geometry
- +7 more
+14 stars
from 391 · score 2.71
85.erayzesen / QuarkPhysics
A 2D Soft Body and Rigid Body Physics Engine.
- 2d-physics-engine
- game-development
- physics-engine
- rigid-bodies
- soft-bodies
- physics-simulation
+14 stars
from 286 · score 2.71
86.romeric / Fastor
A lightweight high performance tensor algebra framework for modern C++
+13 stars
from 832 · score 2.64
87.particle-clicker / particle-clicker
An addictive incremental game that teaches players the history of high energy particle physics
+13 stars
from 675 · score 2.64
88.ReversecLabs / leonidas
Automated Attack Simulation in the Cloud, complete with detection use cases.
+13 stars
from 607 · score 2.64
89.wengong-jin / icml18-jtnn
Junction Tree Variational Autoencoder for Molecular Graph Generation (ICML 2018)
+13 stars
from 551 · score 2.64
90.jimmyorourke / plotlypp
Plotly for C++. A C++ interface to the Plotly.js figure spec, for creating interactive data visualizations.
- charts
- cpp
- graphs
- plotly
- plotting
- visualization
- +4 more
+13 stars
from 135 · score 2.64
91.kreshuklab / panseg
A tool for cell instance aware segmentation in densely packed 3D volumetric images
- segmentation
- deep-learning
- bioinformatics
- neural-network
- bioimage-analysis
- image-segmentation
- +1 more
+13 stars
from 124 · score 2.64
92.cafferychen777 / ChatSpatial
MCP server for spatial transcriptomics analysis through natural language interfaces.
- bioinformatics
- cell-communication
- deconvolution
- machine-learning
- python
- single-cell
- +14 more
+13 stars
from 32 · score 2.64
93.seyonechithrananda / bert-loves-chemistry
bert-loves-chemistry: a repository of HuggingFace models applied on chemical SMILES data for drug design, chemical modelling, etc.
- huggingface
- bert
- chemical-modelling
- chemical-smiles-data
+12 stars
from 491 · score 2.56
94.brndnmtthws / dryoc
Don't Roll Your Own Crypto: fast, type-safe, pure-Rust cryptography with post-quantum support
- libsodium
- crypto
- rust
- cryptography
- cryptography-library
- nacl
- +3 more
+12 stars
from 333 · score 2.56
95.vlang / vtl
The V Tensor Library
- v
- hacktoberfest
- autograd
- deep-learning
- linear-algebra
- machine-learning
- +5 more
+12 stars
from 160 · score 2.56
96.harmonydata / harmony
The Harmony Python library: a research tool for psychologists to harmonise data and questionnaire items. Open source.
- data-harmonization
- data-science
- depression
- harmonisation
- harmonization
- harmony
- +14 more
+12 stars
from 55 · score 2.56
97.aeturrell / skimpy
skimpy is a light weight tool that provides summary statistics about variables in data frames within the console.
- eda
- pandas
- data-science
- exploratory-data-analysis
- summary-statistics
- statistics
+11 stars
from 507 · score 2.48
98.DmitriBogdanov / UTL
Collection of self-contained header-only libraries for C++17
+11 stars
from 326 · score 2.48
99.juan-leon / lowcharts
Tool to draw low-resolution graphs in terminal
- plot
- shell
- troubleshooting
- log
- analysis
- command-line
- +2 more
+11 stars
from 244 · score 2.48
100.PytorchConnectomics / pytorch_connectomics
PyTorch Connectomics: segmentation toolbox for EM connectomics
- computer-vision
- neuroscience
- connectomics
- pytorch
- segmentation
- biomedical-image-processing
- +2 more
+11 stars
from 191 · score 2.48