Trending repositories

1.numpy / numpy

The fundamental package for scientific computing with Python.

• numpy
• python

2.NVIDIA / cutlass

CUDA Templates and Python DSLs for High-Performance Linear Algebra

• cuda
• deep-learning
• deep-learning-library
• cpp
• nvidia
• gpu
• +1 more

3.Z3Prover / z3

The Z3 Theorem Prover

4.isl-org / Open3D

Open3D: A Modern Library for 3D Data Processing

• mesh-processing
• computer-graphics
• opengl
• cpp
• python
• reconstruction
• +14 more

5.sympy / sympy

A computer algebra system written in pure Python

• python
• math
• computer-algebra
• science
• hacktoberfest

6.XAMPPRocky / tokei

Count your code, quickly.

• tokei
• cloc
• badge
• rust
• windows
• linux
• +6 more

7.openrocket / openrocket

Model-rocketry aerodynamics and trajectory simulation software

• aerospace
• flight-simulator
• java
• modeling
• optimization
• rocket
• +3 more

8.Slicer / Slicer

Multi-platform, free open source software for visualization and image computing.

• medical-imaging
• vtk
• itk
• python
• qt
• image-processing
• +14 more

9.RosettaCommons / RFdiffusion

Code for running RFdiffusion

10.g-truc / glm

OpenGL Mathematics (GLM)

• glm
• opengl
• mathematics
• vector
• matrix
• quaternion
• +6 more

11.CGAL / cgal

The public CGAL repository, see the README below

• cgal
• c-plus-plus
• geometry
• algorithms
• library
• cpp
• +11 more

12.biopython / biopython

Official git repository for Biopython (originally converted from CVS)

• python
• bioinformatics
• genomics
• biopython
• protein
• protein-structure
• +3 more

13.chemprop / chemprop

Message Passing Neural Networks for Molecule Property Prediction

• machine-learning
• chemistry
• neural-networks
• drug-discovery

14.Biohub / esm

The repository host gives no description.

15.shopspring / decimal

Arbitrary-precision fixed-point decimal numbers in Go

• go
• decimals
• precision
• money
• bignumber
• golang

16.OpenMDAO / OpenMDAO

OpenMDAO repository.

• nasa
• open-source
• framework
• openmdao
• optimization

17.KratosMultiphysics / Kratos

Kratos Multiphysics (A.K.A Kratos) is a framework for building parallel multi-disciplinary simulation software. Modularity, extensibility and HPC are the main objectives. Kratos has BSD license and is written in C++ with extensive Python interface.

• kratos
• fem
• dem
• parallel-computing
• openmp
• numerical-methods
• +7 more

18.ClawBio / ClawBio

🦖 ClawBio - The first bioinformatics-native AI agent skill library. Local-first. Reproducible. Open. Free.

• ai-agents
• bioinformatics
• equity
• genomics
• local-first
• openclaw
• +2 more

19.dealii / dealii

The development repository for the deal.II finite element library

• finite-elements
• c-plus-plus
• fem
• hpc
• parallel-computing
• scientific-computing
• +1 more

20.BrunoLevy / geogram

a programming library with geometric algorithms

• graphics-libraries
• graphics-programming
• mesh-generation
• mesh-processing
• geometry-processing

21.facebookresearch / pytorch3d

PyTorch3D is FAIR's library of reusable components for deep learning with 3D data

22.brian-team / brian2

Brian is a free, open source simulator for spiking neural networks.

• python
• neuroscience
• science
• differential-equations
• spiking-neural-networks
• biological-simulations
• +5 more

23.SciML / DifferentialEquations.jl

Multi-language suite for high-performance solvers of differential equations and scientific machine learning (SciML) components. Ordinary differential equations (ODEs), stochastic differential equations (SDEs), delay differential equations (DDEs), differential-algebraic equations (DAEs), and more in Julia.

• differential-equations
• differentialequations
• julia
• ode
• sde
• dae
• +14 more

24.instadeepai / nucleotide-transformer

Foundation Models for Genomics & Transcriptomics

• genomics
• deep-learning
• transformer
• dna
• foundation-models
• transcriptomics
• +1 more

25.PixarAnimationStudios / OpenSubdiv

An Open-Source subdivision surface library.

26.mlmed / torchxrayvision

TorchXRayVision: A library of chest X-ray datasets and models. Classifiers, segmentation, and autoencoders.

• medical-imaging
• medical-ai
• deep-learning
• machine-learning
• transfer-learning
• dataset
• +13 more

27.3dmol / 3Dmol.js

WebGL accelerated JavaScript molecular graphics library

• molecular-graphics
• molecular-modeling
• computational-biology
• computational-chemistry

28.mborgerding / kissfft

a Fast Fourier Transform (FFT) library that tries to Keep it Simple, Stupid

29.Reference-LAPACK / lapack

LAPACK development repository

• linear-algebra
• lapack
• blas
• lapacke
• linear-equations
• eigenvalues
• +4 more

30.mahmoodlab / UNI

Pathology Foundation Model - Nature Medicine

• foundation
• foundation-model
• histopathology
• mahmoodlab
• pathology
• uni
• +11 more

31.mahmoud / boltons

🔩 Like builtins, but boltons. 250+ constructs, recipes, and snippets which extend (and rely on nothing but) the Python standard library. Nothing like Michael Bolton.

• python
• utilities
• cache
• data-structures
• statistics
• data-science
• +5 more

32.osrf / gazebo_models

Gazebo database of SDF models. This is a predecessor to https://app.gazebosim.org

• gazebo
• simulation
• robot-simulation
• robotics
• gazebosim
• ros
• +4 more

33.hypre-space / hypre

Parallel solvers for sparse linear systems featuring multigrid methods.

• math-physics
• library
• hpc
• radiuss

34.flame / blis

BLAS-like Library Instantiation Software Framework

• blis
• blas
• blas-libraries
• linear-algebra
• linear-algebra-library
• matrix-multiplication
• +8 more

35.symengine / symengine

SymEngine is a fast symbolic manipulation library, written in C++

• math
• computer-algebra
• c-plus-plus

36.stevengj / nlopt

library for nonlinear optimization, wrapping many algorithms for global and local, constrained or unconstrained, optimization

37.flexible-collision-library / fcl

Flexible Collision Library

• collision
• collision-detection

38.libtom / libtommath

LibTomMath is a free open source portable number theoretic multiple-precision integer library written entirely in C.

• mpi
• libtommath
• c
• math
• multi-precision

39.hjwdzh / QuadriFlow

QuadriFlow: A Scalable and Robust Method for Quadrangulation

• quadriflow
• quad
• remeshing
• quadrangulation
• geometry

40.fo-dicom / fo-dicom

Fellow Oak DICOM for .NET, .NET Core, Universal Windows, Android, iOS, Mono and Unity

• dicom
• netcore
• medical
• medical-imaging
• dot-net
• c-sharp
• +4 more

41.NetTopologySuite / NetTopologySuite

A .NET GIS solution that is fast and reliable for the .NET platform.

• topology
• nts
• sfs
• c-sharp
• library
• jts
• +1 more

42.trilinos / Trilinos

Primary repository for the Trilinos Project

• snl-science-libs
• sandia-national-laboratories
• hpsf
• scientific-computing
• high-performance-computing
• c-plus-plus
• +2 more

43.CMA-ES / pycma

Python implementation of CMA-ES

44.rsvp / fecon235

Notebooks for financial economics. Keywords: Jupyter notebook pandas Federal Reserve FRED Ferbus GDP CPI PCE inflation unemployment wage income debt Case-Shiller housing asset portfolio equities SPX bonds TIPS rates currency FX euro EUR USD JPY yen XAU gold Brent WTI oil Holt-Winters time-series forecasting statistics econometrics

• jupyter-notebook
• pandas
• federal-reserve
• gdp
• inflation
• housing
• +14 more

45.UniMath / UniMath

This rocq library aims to formalize a substantial body of mathematics using the univalent point of view.

• coq
• mathematics
• unimath
• coq-library
• foundations
• rocq
• +1 more

46.usnistgov / fipy

FiPy is a Finite Volume PDE solver written in Python

• scientific-computing
• scientific-computing-with-python
• phase-field
• materials-science
• partial-differential-equations
• shared-memory-parallel
• +2 more

47.CATIA-Systems / FMPy

Simulate Functional Mock-up Units (FMUs) in Python

• fmi
• python
• fmi-standard

48.mahmoodlab / CONCH

Vision-Language Pathology Foundation Model - Nature Medicine

• bioimage-analysis
• bioimage-informatics
• conch
• foundation-model
• health-informatics
• histopathology
• +9 more

49.dcjones / proseg

Probabilistic cell segmentation for in situ spatial transcriptomics

50.nasa / trick

Trick Simulation Environment. Trick provides a common set of simulation capabilities and utilities to build simulations automatically.

51.brandon-rhodes / pyephem

Scientific-grade astronomy routines for Python

52.firedrakeproject / firedrake

Firedrake is an automated system for the portable solution of partial differential equations using the finite element method (FEM)

53.PaddlePaddle / Quantum

The repository host gives no description.

54.rafat / wavelib

C Implementation of 1D and 2D Wavelet Transforms (DWT,SWT and MODWT) along with 1D Wavelet packet Transform and 1D Continuous Wavelet Transform.

• wavelets
• dwt
• continuous-wavelet-transform
• wavelet-packet-trees
• c
• cpp

55.excessive / cpml

Cirno's Perfect Math Library: Just about everything you need for 2D/3D games. Hopefully.

• math

56.samtools / htslib

C library for high-throughput sequencing data formats

• htslib
• bioinformatics
• sam
• bam
• cram
• vcf
• +2 more

57.PetteriAimonen / libfixmath

Cross Platform Fixed Point Maths Library

58.prody / ProDy

A Python Package for Protein Dynamics Analysis

• python
• protein
• dynamics

59.haddocking / pdb-tools

A dependency-free cross-platform swiss army knife for PDB files.

• python
• protein
• pdb
• bioinformatics
• structural-biology
• structural-bioinformatics
• +2 more

60.biolink / biolink-model

Schema and generated objects for biolink data model and upper ontology

• biolink
• monarchinitiative
• gene-ontology
• datamodel
• standard
• specification
• +11 more

61.qhull / qhull

Qhull development for www.qhull.org -- Qhull 2020.2 (8.1-alpha1) at https://github.com/qhull/qhull/wiki

• qhull
• computational-geometry
• convex-hull
• delaunay-triangulation
• voronoi-diagram
• halfspace-intersection
• +3 more

62.dib-lab / khmer

In-memory nucleotide sequence k-mer counting, filtering, graph traversal and more

• dna
• k-mer
• python
• bloom-filter
• count-min-sketch
• graph-traversal
• +1 more

63.chebfun / chebfun

Chebfun: numerical computing with functions.

64.alphaville / optimization-engine

Nonconvex embedded optimization: code generation for fast real-time optimization + ROS support

• embedded-optimization
• nonconvex
• model-predictive-control
• rust-library
• rust
• rust-crate
• +14 more

65.MmgTools / mmg

open source software for bidimensional and tridimensional remeshing

• mesh
• mesh-adaptation
• anisotropic-mesh-adaptation
• isotropic-mesh-adaptation
• mesh-quality-improvement
• surface-improvement
• +11 more

66.ebassi / graphene

A thin layer of graphic data types

• graphics-library
• vector
• transformations
• matrix
• 3d-transformations
• c
• +4 more

67.bp-kelley / descriptastorus

Descriptor computation(chemistry) and (optional) storage for machine learning

68.rocq-community / fourcolor

Formal proof of the Four Color Theorem [maintainer=@ybertot]

• coq
• ssreflect
• mathcomp
• four-color-theorem
• coq-ci

69.math-comp / analysis

Mathematical Components compliant Analysis Library

• rocq
• analysis
• coq
• mathcomp
• ssreflect

70.kharchenkolab / numbat

Haplotype-aware CNV analysis from single-cell RNA-seq, ATAC-seq, and multiome

• cancer-genomics
• cnv-detection
• single-cell
• phylogeny
• single-cell-analysis
• single-cell-rna-seq
• +4 more

71.neslib / FastMath

Fast Math Library for Delphi

• delphi-rtl
• delphi-fastmath
• fastmath
• overloaded-operators
• vectors
• matrix
• +2 more

72.sanderlab / scPerturb

scPerturb: A resource and a python/R tool for single-cell perturbation data

• cite-seq
• database
• perturbation
• scatac-seq
• science
• scrna-seq
• +4 more

73.JuliaPhylo / PhyloNetworks.jl

PhyloNetworks: a julia package with utilities for phylogenetic networks

74.HIPS / Spearmint

Spearmint Bayesian optimization codebase

75.rbdl / rbdl

RBDL is a C++ library that contains some essential and efficient rigid body dynamics algorithms such as the Articulated Body Algorithm (ABA) for forward dynamics, Recursive Newton-Euler Algorithm (RNEA) for inverse dynamics, the Composite Rigid Body Algorithm (CRBA) for the efficient computation of the joint space inertia matrix and is also able to compute forward dynamics with external contact constraints and collision impulses. Furthermore it has some basic support for forward and inverse kinematics.

• articulated-body-algorithm
• inverse-dynamics
• forward-dynamics
• multi-body-dynamics
• inverse-kinematics
• robotics

76.yt-project / yt

Main yt repository

• data
• visualization
• analysis
• python
• scientific-computing
• scientific-visualization
• +6 more

77.pschwllr / MolecularTransformer

The repository host gives no description.

78.Tronald / CoordinateSharp

A library designed to ease geographic coordinate format conversions, and determine sun/moon information in C#

• moon
• coordinates
• longitude
• latitude
• mgrs
• utm
• +13 more

79.microsoft / Quantum-NCArchived

Microsoft Quantum Computing Libraries for noncommercial use

• quantum-development-kit
• quantum
• qdk
• quantum-computing
• qsharp
• python

80.CBICA / CaPTk

Cancer Imaging Phenomics Toolkit (CaPTk) is a software platform to perform image analysis and predictive modeling tasks. Documentation: https://cbica.github.io/CaPTk

• cancer-imaging-research
• radiomics
• radiomics-features
• machine-learning
• cpp
• cpp11
• +14 more

81.mapbox / wagyu

A general library for geometry operations of union, intersections, difference, and xor

• computational-geometry
• union
• intersection
• xor
• geometry
• difference
• +1 more

82.CellProfiler / CellProfiler-Analyst

Open-source software for exploring and analyzing large, high-dimensional image-derived data.

• cellprofiler-analyst
• cellprofiler
• image-analysis
• machine-learning

83.hpddm / hpddm

A framework for high-performance domain decomposition methods.

• c-plus-plus
• linear-algebra
• python
• fortran
• c
• freefem
• +4 more

84.FunctionLab / sei-framework

code to run sei and obtain sei and sequence class predictions

85.JuliaGraphs / MetaGraphs.jl

Graph data structures with multiple heterogeneous metadata for Graphs.jl.

• graph
• graphs
• metadata
• juliagraphs
• datastructures
• data-structures
• +1 more

86.mahmoodlab / MAPS

Machine learning for Analysis of Proteomics in Spatial biology - Nature Communications

• cell-annotation
• multiplexed-imaging
• mpif

87.LigandPro / Matcha

Multi-stage Riemannian flow matching for physically valid molecular docking, with GNINA scoring, PoseBusters filtering, CLI inference, and benchmarks.

• alphafold3
• docking
• drug-design
• drug-discovery
• flowmatching
• gnina
• +8 more

88.Inochi2D / inmath

Games math library for D

• dlang
• math
• nogc