1.Biohub / esm
The repository host gives no description.
+711 stars
from 2,304 · score 6.57
Trending repositories
Ranked by Attention Score: stars gained over the last 180 complete days
20 repositories by Attention Score · May 9, 2026 – Nov 4, 2026 (UTC)
2.ClawBio / ClawBio
🦖 ClawBio - The first bioinformatics-native AI agent skill library. Local-first. Reproducible. Open. Free.
- ai-agents
- bioinformatics
- equity
- genomics
- local-first
- openclaw
- +2 more
+407 stars
from 766 · score 6.01
+279 stars
from 2,842 · score 5.63
4.biopython / biopython
Official git repository for Biopython (originally converted from CVS)
- python
- bioinformatics
- genomics
- biopython
- protein
- protein-structure
- +3 more
+273 stars
from 4,988 · score 5.61
5.instadeepai / nucleotide-transformer
Foundation Models for Genomics & Transcriptomics
- genomics
- deep-learning
- transformer
- dna
- foundation-models
- transcriptomics
- +1 more
+78 stars
from 859 · score 4.37
6.samtools / htslib
C library for high-throughput sequencing data formats
- htslib
- bioinformatics
- sam
- bam
- cram
- vcf
- +2 more
+39 stars
from 917 · score 3.69
7.biolink / biolink-model
Schema and generated objects for biolink data model and upper ontology
- biolink
- monarchinitiative
- gene-ontology
- datamodel
- standard
- specification
- +11 more
+31 stars
from 237 · score 3.47
8.immunogenomics / harmony
Fast, sensitive and accurate integration of single-cell data with Harmony
+30 stars
from 644 · score 3.43
9.dcjones / proseg
Probabilistic cell segmentation for in situ spatial transcriptomics
+29 stars
from 169 · score 3.40
10.sanderlab / scPerturb
scPerturb: A resource and a python/R tool for single-cell perturbation data
+20 stars
from 172 · score 3.04
+17 stars
from 544 · score 2.89
12.kharchenkolab / numbat
Haplotype-aware CNV analysis from single-cell RNA-seq, ATAC-seq, and multiome
- cancer-genomics
- cnv-detection
- single-cell
- phylogeny
- single-cell-analysis
- single-cell-rna-seq
- +4 more
+16 stars
from 217 · score 2.83
13.haddocking / pdb-tools
A dependency-free cross-platform swiss army knife for PDB files.
- python
- protein
- pdb
- bioinformatics
- structural-biology
- structural-bioinformatics
- +2 more
+10 stars
from 451 · score 2.40
14.dib-lab / khmer
In-memory nucleotide sequence k-mer counting, filtering, graph traversal and more
- dna
- k-mer
- python
- bloom-filter
- count-min-sketch
- graph-traversal
- +1 more
+7 stars
from 784 · score 2.08
15.JuliaPhylo / PhyloNetworks.jl
PhyloNetworks: a julia package with utilities for phylogenetic networks
+6 stars
from 171 · score 1.95
16.FunctionLab / sei-framework
code to run sei and obtain sei and sequence class predictions
+6 stars
from 113 · score 1.95
+4 stars
from 246 · score 1.61
+3 stars
from 218 · score 1.39
19.mahmoodlab / MAPS
Machine learning for Analysis of Proteomics in Spatial biology - Nature Communications
- cell-annotation
- multiplexed-imaging
- mpif
+3 stars
from 64 · score 1.39
20.CellProfiler / CellProfiler-Analyst
Open-source software for exploring and analyzing large, high-dimensional image-derived data.
- cellprofiler-analyst
- cellprofiler
- image-analysis
- machine-learning
+2 stars
from 170 · score 1.10