Trending repositories
Ranked by Attention Score: stars gained over the last 180 complete days
90 repositories by Attention Score · May 8, 2026 – Nov 3, 2026 (UTC)
2.NVIDIA / cutlass
CUDA Templates and Python DSLs for High-Performance Linear Algebra
- cuda
- deep-learning
- deep-learning-library
- cpp
- nvidia
- gpu
- +1 more
3.XAMPPRocky / tokei
Count your code, quickly.
5.Biohub / esm
The repository host gives no description.
6.isl-org / Open3D
Open3D: A Modern Library for 3D Data Processing
- mesh-processing
- computer-graphics
- opengl
- cpp
- python
- reconstruction
- +14 more
7.sympy / sympy
A computer algebra system written in pure Python
- python
- math
- computer-algebra
- science
- hacktoberfest
9.ClawBio / ClawBio
🦖 ClawBio - The first bioinformatics-native AI agent skill library. Local-first. Reproducible. Open. Free.
- ai-agents
- bioinformatics
- equity
- genomics
- local-first
- openclaw
- +2 more
10.openrocket / openrocket
Model-rocketry aerodynamics and trajectory simulation software
- aerospace
- flight-simulator
- java
- modeling
- optimization
- rocket
- +3 more
12.Slicer / Slicer
Multi-platform, free open source software for visualization and image computing.
- medical-imaging
- vtk
- itk
- python
- qt
- image-processing
- +14 more
13.biopython / biopython
Official git repository for Biopython (originally converted from CVS)
- python
- bioinformatics
- genomics
- biopython
- protein
- protein-structure
- +3 more
14.CGAL / cgal
The public CGAL repository, see the README below
- cgal
- c-plus-plus
- geometry
- algorithms
- library
- cpp
- +11 more
15.shopspring / decimal
Arbitrary-precision fixed-point decimal numbers in Go
- go
- decimals
- precision
- money
- bignumber
- golang
16.chemprop / chemprop
Message Passing Neural Networks for Molecule Property Prediction
- machine-learning
- chemistry
- neural-networks
- drug-discovery
17.facebookresearch / pytorch3d
PyTorch3D is FAIR's library of reusable components for deep learning with 3D data
18.BrunoLevy / geogram
a programming library with geometric algorithms
- graphics-libraries
- graphics-programming
- mesh-generation
- mesh-processing
- geometry-processing
19.KratosMultiphysics / Kratos
Kratos Multiphysics (A.K.A Kratos) is a framework for building parallel multi-disciplinary simulation software. Modularity, extensibility and HPC are the main objectives. Kratos has BSD license and is written in C++ with extensive Python interface.
- kratos
- fem
- dem
- parallel-computing
- openmp
- numerical-methods
- +7 more
20.mborgerding / kissfft
a Fast Fourier Transform (FFT) library that tries to Keep it Simple, Stupid
21.osrf / gazebo_models
Gazebo database of SDF models. This is a predecessor to https://app.gazebosim.org
- gazebo
- simulation
- robot-simulation
- robotics
- gazebosim
- ros
- +4 more
23.SciML / DifferentialEquations.jl
Multi-language suite for high-performance solvers of differential equations and scientific machine learning (SciML) components. Ordinary differential equations (ODEs), stochastic differential equations (SDEs), delay differential equations (DDEs), differential-algebraic equations (DAEs), and more in Julia.
- differential-equations
- differentialequations
- julia
- ode
- sde
- dae
- +14 more
24.dealii / dealii
The development repository for the deal.II finite element library
- finite-elements
- c-plus-plus
- fem
- hpc
- parallel-computing
- scientific-computing
- +1 more
25.brian-team / brian2
Brian is a free, open source simulator for spiking neural networks.
- python
- neuroscience
- science
- differential-equations
- spiking-neural-networks
- biological-simulations
- +5 more
26.R74nCom / sandboxels
In-browser falling-sand simulation game with over 500 elements and thousands of reactions.
- browser-game
- cellular-automata
- cellular-automaton
- chemistry
- chemistry-lab
- falling-sand
- +14 more
27.stevengj / nlopt
library for nonlinear optimization, wrapping many algorithms for global and local, constrained or unconstrained, optimization
29.mahmoud / boltons
🔩 Like builtins, but boltons. 250+ constructs, recipes, and snippets which extend (and rely on nothing but) the Python standard library. Nothing like Michael Bolton.
- python
- utilities
- cache
- data-structures
- statistics
- data-science
- +5 more
30.Reference-LAPACK / lapack
LAPACK development repository
- linear-algebra
- lapack
- blas
- lapacke
- linear-equations
- eigenvalues
- +4 more
31.flame / blis
BLAS-like Library Instantiation Software Framework
- blis
- blas
- blas-libraries
- linear-algebra
- linear-algebra-library
- matrix-multiplication
- +8 more
32.mahmoodlab / UNI
Pathology Foundation Model - Nature Medicine
- foundation
- foundation-model
- histopathology
- mahmoodlab
- pathology
- uni
- +11 more
33.mlmed / torchxrayvision
TorchXRayVision: A library of chest X-ray datasets and models. Classifiers, segmentation, and autoencoders.
- medical-imaging
- medical-ai
- deep-learning
- machine-learning
- transfer-learning
- dataset
- +13 more
34.instadeepai / nucleotide-transformer
Foundation Models for Genomics & Transcriptomics
- genomics
- deep-learning
- transformer
- dna
- foundation-models
- transcriptomics
- +1 more
35.symengine / symengine
SymEngine is a fast symbolic manipulation library, written in C++
- math
- computer-algebra
- c-plus-plus
36.3dmol / 3Dmol.js
WebGL accelerated JavaScript molecular graphics library
- molecular-graphics
- molecular-modeling
- computational-biology
- computational-chemistry
37.hjwdzh / QuadriFlow
QuadriFlow: A Scalable and Robust Method for Quadrangulation
- quadriflow
- quad
- remeshing
- quadrangulation
- geometry
38.trilinos / Trilinos
Primary repository for the Trilinos Project
- snl-science-libs
- sandia-national-laboratories
- hpsf
- scientific-computing
- high-performance-computing
- c-plus-plus
- +2 more
39.NetTopologySuite / NetTopologySuite
A .NET GIS solution that is fast and reliable for the .NET platform.
- topology
- nts
- sfs
- c-sharp
- library
- jts
- +1 more
41.PixarAnimationStudios / OpenSubdiv
An Open-Source subdivision surface library.
42.nasa / trick
Trick Simulation Environment. Trick provides a common set of simulation capabilities and utilities to build simulations automatically.
43.hypre-space / hypre
Parallel solvers for sparse linear systems featuring multigrid methods.
- math-physics
- library
- hpc
- radiuss
44.samtools / htslib
C library for high-throughput sequencing data formats
- htslib
- bioinformatics
- sam
- bam
- cram
- vcf
- +2 more
45.firedrakeproject / firedrake
Firedrake is an automated system for the portable solution of partial differential equations using the finite element method (FEM)
46.usnistgov / fipy
FiPy is a Finite Volume PDE solver written in Python
- scientific-computing
- scientific-computing-with-python
- phase-field
- materials-science
- partial-differential-equations
- shared-memory-parallel
- +2 more
48.MmgTools / mmg
open source software for bidimensional and tridimensional remeshing
- mesh
- mesh-adaptation
- anisotropic-mesh-adaptation
- isotropic-mesh-adaptation
- mesh-quality-improvement
- surface-improvement
- +11 more
49.fo-dicom / fo-dicom
Fellow Oak DICOM for .NET, .NET Core, Universal Windows, Android, iOS, Mono and Unity
- dicom
- netcore
- medical
- medical-imaging
- dot-net
- c-sharp
- +4 more
50.libtom / libtommath
LibTomMath is a free open source portable number theoretic multiple-precision integer library written entirely in C.
- mpi
- libtommath
- c
- math
- multi-precision
51.immunogenomics / harmony
Fast, sensitive and accurate integration of single-cell data with Harmony
52.dylanrees / citizen-science
🔬 A repository of resources related to citizen, community-based and/or non-institutional science
- citizen-science
- science
- lab-equipment
- scientific
- activism
53.PetteriAimonen / libfixmath
Cross Platform Fixed Point Maths Library
54.UniMath / UniMath
This rocq library aims to formalize a substantial body of mathematics using the univalent point of view.
- coq
- mathematics
- unimath
- coq-library
- foundations
- rocq
- +1 more
55.alphaville / optimization-engine
Nonconvex embedded optimization: code generation for fast real-time optimization + ROS support
- embedded-optimization
- nonconvex
- model-predictive-control
- rust-library
- rust
- rust-crate
- +14 more
56.rbdl / rbdl
RBDL is a C++ library that contains some essential and efficient rigid body dynamics algorithms such as the Articulated Body Algorithm (ABA) for forward dynamics, Recursive Newton-Euler Algorithm (RNEA) for inverse dynamics, the Composite Rigid Body Algorithm (CRBA) for the efficient computation of the joint space inertia matrix and is also able to compute forward dynamics with external contact constraints and collision impulses. Furthermore it has some basic support for forward and inverse kinematics.
- articulated-body-algorithm
- inverse-dynamics
- forward-dynamics
- multi-body-dynamics
- inverse-kinematics
- robotics
57.sanderlab / scPerturb
scPerturb: A resource and a python/R tool for single-cell perturbation data
58.rsvp / fecon235
Notebooks for financial economics. Keywords: Jupyter notebook pandas Federal Reserve FRED Ferbus GDP CPI PCE inflation unemployment wage income debt Case-Shiller housing asset portfolio equities SPX bonds TIPS rates currency FX euro EUR USD JPY yen XAU gold Brent WTI oil Holt-Winters time-series forecasting statistics econometrics
- jupyter-notebook
- pandas
- federal-reserve
- gdp
- inflation
- housing
- +14 more
59.qhull / qhull
Qhull development for www.qhull.org -- Qhull 2020.2 (8.1-alpha1) at https://github.com/qhull/qhull/wiki
- qhull
- computational-geometry
- convex-hull
- delaunay-triangulation
- voronoi-diagram
- halfspace-intersection
- +3 more
60.brandon-rhodes / pyephem
Scientific-grade astronomy routines for Python
61.ebassi / graphene
A thin layer of graphic data types
- graphics-library
- vector
- transformations
- matrix
- 3d-transformations
- c
- +4 more
62.chebfun / chebfun
Chebfun: numerical computing with functions.
63.inducer / meshpy
2D/3D simplicial mesh generator interface for Python (Triangle, TetGen, gmsh)
- python
- mesh-generation
- scientific-computing
- triangle
- tetgen
- wrapper
- +1 more
64.LigandPro / Matcha
Multi-stage Riemannian flow matching for physically valid molecular docking, with GNINA scoring, PoseBusters filtering, CLI inference, and benchmarks.
- alphafold3
- docking
- drug-design
- drug-discovery
- flowmatching
- gnina
- +8 more
65.GlPortal / glPortal
:video_game: Open Source teleportation based first person puzzle-platformer
66.excessive / cpml
Cirno's Perfect Math Library: Just about everything you need for 2D/3D games. Hopefully.
68.PaddlePaddle / Quantum
The repository host gives no description.
69.spamegg1 / Math-for-CS-solutions
Solutions to In-Class questions, Problem Sets and Exams of MIT Mathematics for Computer Science 2015 (same as 2019 Open Learning Library)
- calculus
- counting
- functions
- graph
- graph-theory
- induction
- +11 more
70.yt-project / yt
Main yt repository
- data
- visualization
- analysis
- python
- scientific-computing
- scientific-visualization
- +6 more
71.haddocking / pdb-tools
A dependency-free cross-platform swiss army knife for PDB files.
- python
- protein
- pdb
- bioinformatics
- structural-biology
- structural-bioinformatics
- +2 more
72.blinry / gish
Open Source version of the award-winning physics platformer
73.banterle / HDR_Toolbox
HDR Toolbox for processing High Dynamic Range (HDR) images into MATLAB and Octave
- hdr
- tone-mapping
- inverse-tonemapping
- tonemapping
- imaging
- reverse-tone-mapping
- +4 more
75.enlite-ai / maze
Maze Applied Reinforcement Learning Framework
76.dib-lab / khmer
In-memory nucleotide sequence k-mer counting, filtering, graph traversal and more
- dna
- k-mer
- python
- bloom-filter
- count-min-sketch
- graph-traversal
- +1 more
77.tencent-ailab / grover
This is a Pytorch implementation of the paper: Self-Supervised Graph Transformer on Large-Scale Molecular Data
78.bp-kelley / descriptastorus
Descriptor computation(chemistry) and (optional) storage for machine learning
79.JuliaPhylo / PhyloNetworks.jl
PhyloNetworks: a julia package with utilities for phylogenetic networks
80.Unidata / netcdf-fortran
Official GitHub repository for netCDF-Fortran libraries, which depend on the netCDF C library. Install the netCDF C library first.
- netcdf-fortran
- unidata
- netcdf-library
- dataset
- hacktoberfest
81.mapbox / wagyu
A general library for geometry operations of union, intersections, difference, and xor
- computational-geometry
- union
- intersection
- xor
- geometry
- difference
- +1 more
82.aelefebv / nellie
Nellie: Automated organelle segmentation, tracking, and hierarchical feature extraction in 2D/3D live-cell microscopy
- biology
- fluorescence
- image-analysis
- image-processing
- machine-learning
- microscopy
- +3 more
84.xtreemze / defend
Procedural Cross-Platform 3D Tower Defense WebGame with Physics and AI and Procedural Sound
- babylonjs
- javascript
- typescript
- projectiles
- towers
85.rii-mango / Papaya
A pure JavaScript medical research image viewer.
86.OpenSimulationInterface / open-simulation-interface
A generic interface for the environmental perception of automated driving functions in virtual scenarios.
- asam
- osi
- open-simulation-interface
- simulation
87.ekrich / sblas
Scala Native BLAS (Basic Linear Algebra Subprograms) supporting Linux and macOS
- scala
- scala-native
- math
- linear-algebra
- blas
- linux
- +1 more
88.fkromer / awesome-gazeboArchived
Gazebo, the simulation framework for ROS1 and ROS2 is awesome!
89.szhorvat / IGraphM
IGraph/M is the igraph interface for Mathematica
- igraph
- mathematica
- mathematics
- network-graph
- graph-theory
- raspberry-pi
- +3 more