Trending repositories
Ranked by Attention Score: stars gained over the last 90 complete days
1–100 of 102 by Attention Score · Aug 7, 2026 – Nov 4, 2026 (UTC)
2.NVIDIA / cutlass
CUDA Templates and Python DSLs for High-Performance Linear Algebra
- cuda
- deep-learning
- deep-learning-library
- cpp
- nvidia
- gpu
- +1 more
4.isl-org / Open3D
Open3D: A Modern Library for 3D Data Processing
- mesh-processing
- computer-graphics
- opengl
- cpp
- python
- reconstruction
- +14 more
5.XAMPPRocky / tokei
Count your code, quickly.
6.sympy / sympy
A computer algebra system written in pure Python
- python
- math
- computer-algebra
- science
- hacktoberfest
8.openrocket / openrocket
Model-rocketry aerodynamics and trajectory simulation software
- aerospace
- flight-simulator
- java
- modeling
- optimization
- rocket
- +3 more
9.Slicer / Slicer
Multi-platform, free open source software for visualization and image computing.
- medical-imaging
- vtk
- itk
- python
- qt
- image-processing
- +14 more
10.Biohub / esm
The repository host gives no description.
12.biopython / biopython
Official git repository for Biopython (originally converted from CVS)
- python
- bioinformatics
- genomics
- biopython
- protein
- protein-structure
- +3 more
13.CGAL / cgal
The public CGAL repository, see the README below
- cgal
- c-plus-plus
- geometry
- algorithms
- library
- cpp
- +11 more
14.ClawBio / ClawBio
🦖 ClawBio - The first bioinformatics-native AI agent skill library. Local-first. Reproducible. Open. Free.
- ai-agents
- bioinformatics
- equity
- genomics
- local-first
- openclaw
- +2 more
15.BrunoLevy / geogram
a programming library with geometric algorithms
- graphics-libraries
- graphics-programming
- mesh-generation
- mesh-processing
- geometry-processing
16.chemprop / chemprop
Message Passing Neural Networks for Molecule Property Prediction
- machine-learning
- chemistry
- neural-networks
- drug-discovery
17.KratosMultiphysics / Kratos
Kratos Multiphysics (A.K.A Kratos) is a framework for building parallel multi-disciplinary simulation software. Modularity, extensibility and HPC are the main objectives. Kratos has BSD license and is written in C++ with extensive Python interface.
- kratos
- fem
- dem
- parallel-computing
- openmp
- numerical-methods
- +7 more
18.shopspring / decimal
Arbitrary-precision fixed-point decimal numbers in Go
- go
- decimals
- precision
- money
- bignumber
- golang
19.facebookresearch / pytorch3d
PyTorch3D is FAIR's library of reusable components for deep learning with 3D data
20.brian-team / brian2
Brian is a free, open source simulator for spiking neural networks.
- python
- neuroscience
- science
- differential-equations
- spiking-neural-networks
- biological-simulations
- +5 more
22.dealii / dealii
The development repository for the deal.II finite element library
- finite-elements
- c-plus-plus
- fem
- hpc
- parallel-computing
- scientific-computing
- +1 more
23.osrf / gazebo_models
Gazebo database of SDF models. This is a predecessor to https://app.gazebosim.org
- gazebo
- simulation
- robot-simulation
- robotics
- gazebosim
- ros
- +4 more
24.mahmoud / boltons
🔩 Like builtins, but boltons. 250+ constructs, recipes, and snippets which extend (and rely on nothing but) the Python standard library. Nothing like Michael Bolton.
- python
- utilities
- cache
- data-structures
- statistics
- data-science
- +5 more
25.SciML / DifferentialEquations.jl
Multi-language suite for high-performance solvers of differential equations and scientific machine learning (SciML) components. Ordinary differential equations (ODEs), stochastic differential equations (SDEs), delay differential equations (DDEs), differential-algebraic equations (DAEs), and more in Julia.
- differential-equations
- differentialequations
- julia
- ode
- sde
- dae
- +14 more
26.Reference-LAPACK / lapack
LAPACK development repository
- linear-algebra
- lapack
- blas
- lapacke
- linear-equations
- eigenvalues
- +4 more
27.mborgerding / kissfft
a Fast Fourier Transform (FFT) library that tries to Keep it Simple, Stupid
28.stevengj / nlopt
library for nonlinear optimization, wrapping many algorithms for global and local, constrained or unconstrained, optimization
29.3dmol / 3Dmol.js
WebGL accelerated JavaScript molecular graphics library
- molecular-graphics
- molecular-modeling
- computational-biology
- computational-chemistry
30.mahmoodlab / UNI
Pathology Foundation Model - Nature Medicine
- foundation
- foundation-model
- histopathology
- mahmoodlab
- pathology
- uni
- +11 more
31.mlmed / torchxrayvision
TorchXRayVision: A library of chest X-ray datasets and models. Classifiers, segmentation, and autoencoders.
- medical-imaging
- medical-ai
- deep-learning
- machine-learning
- transfer-learning
- dataset
- +13 more
32.flame / blis
BLAS-like Library Instantiation Software Framework
- blis
- blas
- blas-libraries
- linear-algebra
- linear-algebra-library
- matrix-multiplication
- +8 more
33.instadeepai / nucleotide-transformer
Foundation Models for Genomics & Transcriptomics
- genomics
- deep-learning
- transformer
- dna
- foundation-models
- transcriptomics
- +1 more
34.hjwdzh / QuadriFlow
QuadriFlow: A Scalable and Robust Method for Quadrangulation
- quadriflow
- quad
- remeshing
- quadrangulation
- geometry
36.trilinos / Trilinos
Primary repository for the Trilinos Project
- snl-science-libs
- sandia-national-laboratories
- hpsf
- scientific-computing
- high-performance-computing
- c-plus-plus
- +2 more
37.symengine / symengine
SymEngine is a fast symbolic manipulation library, written in C++
- math
- computer-algebra
- c-plus-plus
38.hypre-space / hypre
Parallel solvers for sparse linear systems featuring multigrid methods.
- math-physics
- library
- hpc
- radiuss
39.PixarAnimationStudios / OpenSubdiv
An Open-Source subdivision surface library.
40.firedrakeproject / firedrake
Firedrake is an automated system for the portable solution of partial differential equations using the finite element method (FEM)
41.nasa / trick
Trick Simulation Environment. Trick provides a common set of simulation capabilities and utilities to build simulations automatically.
42.NetTopologySuite / NetTopologySuite
A .NET GIS solution that is fast and reliable for the .NET platform.
- topology
- nts
- sfs
- c-sharp
- library
- jts
- +1 more
44.mahmoodlab / CONCH
Vision-Language Pathology Foundation Model - Nature Medicine
- bioimage-analysis
- bioimage-informatics
- conch
- foundation-model
- health-informatics
- histopathology
- +9 more
46.libtom / libtommath
LibTomMath is a free open source portable number theoretic multiple-precision integer library written entirely in C.
- mpi
- libtommath
- c
- math
- multi-precision
47.samtools / htslib
C library for high-throughput sequencing data formats
- htslib
- bioinformatics
- sam
- bam
- cram
- vcf
- +2 more
48.dcjones / proseg
Probabilistic cell segmentation for in situ spatial transcriptomics
49.fo-dicom / fo-dicom
Fellow Oak DICOM for .NET, .NET Core, Universal Windows, Android, iOS, Mono and Unity
- dicom
- netcore
- medical
- medical-imaging
- dot-net
- c-sharp
- +4 more
50.rsvp / fecon235
Notebooks for financial economics. Keywords: Jupyter notebook pandas Federal Reserve FRED Ferbus GDP CPI PCE inflation unemployment wage income debt Case-Shiller housing asset portfolio equities SPX bonds TIPS rates currency FX euro EUR USD JPY yen XAU gold Brent WTI oil Holt-Winters time-series forecasting statistics econometrics
- jupyter-notebook
- pandas
- federal-reserve
- gdp
- inflation
- housing
- +14 more
51.PetteriAimonen / libfixmath
Cross Platform Fixed Point Maths Library
52.immunogenomics / harmony
Fast, sensitive and accurate integration of single-cell data with Harmony
53.usnistgov / fipy
FiPy is a Finite Volume PDE solver written in Python
- scientific-computing
- scientific-computing-with-python
- phase-field
- materials-science
- partial-differential-equations
- shared-memory-parallel
- +2 more
54.rbdl / rbdl
RBDL is a C++ library that contains some essential and efficient rigid body dynamics algorithms such as the Articulated Body Algorithm (ABA) for forward dynamics, Recursive Newton-Euler Algorithm (RNEA) for inverse dynamics, the Composite Rigid Body Algorithm (CRBA) for the efficient computation of the joint space inertia matrix and is also able to compute forward dynamics with external contact constraints and collision impulses. Furthermore it has some basic support for forward and inverse kinematics.
- articulated-body-algorithm
- inverse-dynamics
- forward-dynamics
- multi-body-dynamics
- inverse-kinematics
- robotics
55.MmgTools / mmg
open source software for bidimensional and tridimensional remeshing
- mesh
- mesh-adaptation
- anisotropic-mesh-adaptation
- isotropic-mesh-adaptation
- mesh-quality-improvement
- surface-improvement
- +11 more
56.biolink / biolink-model
Schema and generated objects for biolink data model and upper ontology
- biolink
- monarchinitiative
- gene-ontology
- datamodel
- standard
- specification
- +11 more
57.sanderlab / scPerturb
scPerturb: A resource and a python/R tool for single-cell perturbation data
58.UniMath / UniMath
This rocq library aims to formalize a substantial body of mathematics using the univalent point of view.
- coq
- mathematics
- unimath
- coq-library
- foundations
- rocq
- +1 more
59.brandon-rhodes / pyephem
Scientific-grade astronomy routines for Python
60.alphaville / optimization-engine
Nonconvex embedded optimization: code generation for fast real-time optimization + ROS support
- embedded-optimization
- nonconvex
- model-predictive-control
- rust-library
- rust
- rust-crate
- +14 more
61.ebassi / graphene
A thin layer of graphic data types
- graphics-library
- vector
- transformations
- matrix
- 3d-transformations
- c
- +4 more
62.anpa1200 / adversarygraph
Self-hosted AI-assisted CTI-to-detection workbench for ATT&CK mapping, IOC/CVE intelligence, Threat Radar, malware triage, Attack Simulation, and SIEM validation.
- cybersecurity
- docker
- fastapi
- llm
- mitre-attack
- react
- +14 more
63.inducer / meshpy
2D/3D simplicial mesh generator interface for Python (Triangle, TetGen, gmsh)
- python
- mesh-generation
- scientific-computing
- triangle
- tetgen
- wrapper
- +1 more
64.kharchenkolab / numbat
Haplotype-aware CNV analysis from single-cell RNA-seq, ATAC-seq, and multiome
- cancer-genomics
- cnv-detection
- single-cell
- phylogeny
- single-cell-analysis
- single-cell-rna-seq
- +4 more
66.rocq-community / fourcolor
Formal proof of the Four Color Theorem [maintainer=@ybertot]
- coq
- ssreflect
- mathcomp
- four-color-theorem
- coq-ci
67.chebfun / chebfun
Chebfun: numerical computing with functions.
68.lukaszcz / coqhammer
CoqHammer: An Automated Reasoning Hammer Tool for Rocq - Proof Automation for Dependent Type Theory
- coq
- hammer
- automation
- proof-search
- theorem-prover
- verification
- +3 more
69.hpddm / hpddm
A framework for high-performance domain decomposition methods.
- c-plus-plus
- linear-algebra
- python
- fortran
- c
- freefem
- +4 more
70.qhull / qhull
Qhull development for www.qhull.org -- Qhull 2020.2 (8.1-alpha1) at https://github.com/qhull/qhull/wiki
- qhull
- computational-geometry
- convex-hull
- delaunay-triangulation
- voronoi-diagram
- halfspace-intersection
- +3 more
71.PaddlePaddle / Quantum
The repository host gives no description.
72.haddocking / pdb-tools
A dependency-free cross-platform swiss army knife for PDB files.
- python
- protein
- pdb
- bioinformatics
- structural-biology
- structural-bioinformatics
- +2 more
73.rafat / wavelib
C Implementation of 1D and 2D Wavelet Transforms (DWT,SWT and MODWT) along with 1D Wavelet packet Transform and 1D Continuous Wavelet Transform.
- wavelets
- dwt
- continuous-wavelet-transform
- wavelet-packet-trees
- c
- cpp
74.Tronald / CoordinateSharp
A library designed to ease geographic coordinate format conversions, and determine sun/moon information in C#
- moon
- coordinates
- longitude
- latitude
- mgrs
- utm
- +13 more
75.LigandPro / Matcha
Multi-stage Riemannian flow matching for physically valid molecular docking, with GNINA scoring, PoseBusters filtering, CLI inference, and benchmarks.
- alphafold3
- docking
- drug-design
- drug-discovery
- flowmatching
- gnina
- +8 more
76.dib-lab / khmer
In-memory nucleotide sequence k-mer counting, filtering, graph traversal and more
- dna
- k-mer
- python
- bloom-filter
- count-min-sketch
- graph-traversal
- +1 more
77.yt-project / yt
Main yt repository
- data
- visualization
- analysis
- python
- scientific-computing
- scientific-visualization
- +6 more
78.excessive / cpml
Cirno's Perfect Math Library: Just about everything you need for 2D/3D games. Hopefully.
79.xiaoyeli / superlu
Supernodal sparse direct solver. https://portal.nersc.gov/project/sparse/superlu/
80.neslib / FastMath
Fast Math Library for Delphi
- delphi-rtl
- delphi-fastmath
- fastmath
- overloaded-operators
- vectors
- matrix
- +2 more
81.FunctionLab / sei-framework
code to run sei and obtain sei and sequence class predictions
83.math-comp / analysis
Mathematical Components compliant Analysis Library
- rocq
- analysis
- coq
- mathcomp
- ssreflect
84.mapbox / wagyu
A general library for geometry operations of union, intersections, difference, and xor
- computational-geometry
- union
- intersection
- xor
- geometry
- difference
- +1 more
85.HALFpipe / HALFpipe
ENIGMA HALFpipe is a user-friendly software that facilitates reproducible analysis of fMRI data
- neuroimaging
- reproducibility
- pipeline
- meta-analysis
- bids
- fmri
86.pschwllr / MolecularTransformer
The repository host gives no description.
87.pymor / pymor
pyMOR - Model Order Reduction with Python
- python
- model-reduction
- model-order-reduction
- control-systems
- state-space
- data-driven
- +8 more
88.bp-kelley / descriptastorus
Descriptor computation(chemistry) and (optional) storage for machine learning
91.microsoft / Quantum-NCArchived
Microsoft Quantum Computing Libraries for noncommercial use
- quantum-development-kit
- quantum
- qdk
- quantum-computing
- qsharp
- python
92.JuliaPhylo / PhyloNetworks.jl
PhyloNetworks: a julia package with utilities for phylogenetic networks
93.CellProfiler / CellProfiler-Analyst
Open-source software for exploring and analyzing large, high-dimensional image-derived data.
- cellprofiler-analyst
- cellprofiler
- image-analysis
- machine-learning
94.JuliaGraphs / NetworkLayout.jl
Layout algorithms for graphs and trees in pure Julia.
- graph-visualization
95.ekrich / sblas
Scala Native BLAS (Basic Linear Algebra Subprograms) supporting Linux and macOS
- scala
- scala-native
- math
- linear-algebra
- blas
- linux
- +1 more
96.xtreemze / defend
Procedural Cross-Platform 3D Tower Defense WebGame with Physics and AI and Procedural Sound
- babylonjs
- javascript
- typescript
- projectiles
- towers
97.OpenSimulationInterface / open-simulation-interface
A generic interface for the environmental perception of automated driving functions in virtual scenarios.
- asam
- osi
- open-simulation-interface
- simulation
99.CBICA / CaPTk
Cancer Imaging Phenomics Toolkit (CaPTk) is a software platform to perform image analysis and predictive modeling tasks. Documentation: https://cbica.github.io/CaPTk
- cancer-imaging-research
- radiomics
- radiomics-features
- machine-learning
- cpp
- cpp11
- +14 more
100.libmir / mir-algorithm
Dlang Core Library
- ndslice
- iterator
- range
- algorithms
- multidimensionality
- multidimensional-arrays