Trending repositories
Ranked by Attention Score: stars gained over the last 30 complete days
81 repositories by Attention Score · Oct 6, 2026 – Nov 4, 2026 (UTC)
2.NVIDIA / cutlass
CUDA Templates and Python DSLs for High-Performance Linear Algebra
- cuda
- deep-learning
- deep-learning-library
- cpp
- nvidia
- gpu
- +1 more
3.isl-org / Open3D
Open3D: A Modern Library for 3D Data Processing
- mesh-processing
- computer-graphics
- opengl
- cpp
- python
- reconstruction
- +14 more
5.sympy / sympy
A computer algebra system written in pure Python
- python
- math
- computer-algebra
- science
- hacktoberfest
6.XAMPPRocky / tokei
Count your code, quickly.
7.Slicer / Slicer
Multi-platform, free open source software for visualization and image computing.
- medical-imaging
- vtk
- itk
- python
- qt
- image-processing
- +14 more
8.openrocket / openrocket
Model-rocketry aerodynamics and trajectory simulation software
- aerospace
- flight-simulator
- java
- modeling
- optimization
- rocket
- +3 more
11.CGAL / cgal
The public CGAL repository, see the README below
- cgal
- c-plus-plus
- geometry
- algorithms
- library
- cpp
- +11 more
12.biopython / biopython
Official git repository for Biopython (originally converted from CVS)
- python
- bioinformatics
- genomics
- biopython
- protein
- protein-structure
- +3 more
13.chemprop / chemprop
Message Passing Neural Networks for Molecule Property Prediction
- machine-learning
- chemistry
- neural-networks
- drug-discovery
14.Biohub / esm
The repository host gives no description.
15.shopspring / decimal
Arbitrary-precision fixed-point decimal numbers in Go
- go
- decimals
- precision
- money
- bignumber
- golang
17.KratosMultiphysics / Kratos
Kratos Multiphysics (A.K.A Kratos) is a framework for building parallel multi-disciplinary simulation software. Modularity, extensibility and HPC are the main objectives. Kratos has BSD license and is written in C++ with extensive Python interface.
- kratos
- fem
- dem
- parallel-computing
- openmp
- numerical-methods
- +7 more
18.dealii / dealii
The development repository for the deal.II finite element library
- finite-elements
- c-plus-plus
- fem
- hpc
- parallel-computing
- scientific-computing
- +1 more
19.ClawBio / ClawBio
🦖 ClawBio - The first bioinformatics-native AI agent skill library. Local-first. Reproducible. Open. Free.
- ai-agents
- bioinformatics
- equity
- genomics
- local-first
- openclaw
- +2 more
20.BrunoLevy / geogram
a programming library with geometric algorithms
- graphics-libraries
- graphics-programming
- mesh-generation
- mesh-processing
- geometry-processing
21.facebookresearch / pytorch3d
PyTorch3D is FAIR's library of reusable components for deep learning with 3D data
22.brian-team / brian2
Brian is a free, open source simulator for spiking neural networks.
- python
- neuroscience
- science
- differential-equations
- spiking-neural-networks
- biological-simulations
- +5 more
23.SciML / DifferentialEquations.jl
Multi-language suite for high-performance solvers of differential equations and scientific machine learning (SciML) components. Ordinary differential equations (ODEs), stochastic differential equations (SDEs), delay differential equations (DDEs), differential-algebraic equations (DAEs), and more in Julia.
- differential-equations
- differentialequations
- julia
- ode
- sde
- dae
- +14 more
24.mahmoud / boltons
🔩 Like builtins, but boltons. 250+ constructs, recipes, and snippets which extend (and rely on nothing but) the Python standard library. Nothing like Michael Bolton.
- python
- utilities
- cache
- data-structures
- statistics
- data-science
- +5 more
25.PixarAnimationStudios / OpenSubdiv
An Open-Source subdivision surface library.
26.instadeepai / nucleotide-transformer
Foundation Models for Genomics & Transcriptomics
- genomics
- deep-learning
- transformer
- dna
- foundation-models
- transcriptomics
- +1 more
27.mlmed / torchxrayvision
TorchXRayVision: A library of chest X-ray datasets and models. Classifiers, segmentation, and autoencoders.
- medical-imaging
- medical-ai
- deep-learning
- machine-learning
- transfer-learning
- dataset
- +13 more
28.3dmol / 3Dmol.js
WebGL accelerated JavaScript molecular graphics library
- molecular-graphics
- molecular-modeling
- computational-biology
- computational-chemistry
29.mahmoodlab / UNI
Pathology Foundation Model - Nature Medicine
- foundation
- foundation-model
- histopathology
- mahmoodlab
- pathology
- uni
- +11 more
30.mborgerding / kissfft
a Fast Fourier Transform (FFT) library that tries to Keep it Simple, Stupid
31.Reference-LAPACK / lapack
LAPACK development repository
- linear-algebra
- lapack
- blas
- lapacke
- linear-equations
- eigenvalues
- +4 more
32.osrf / gazebo_models
Gazebo database of SDF models. This is a predecessor to https://app.gazebosim.org
- gazebo
- simulation
- robot-simulation
- robotics
- gazebosim
- ros
- +4 more
33.hypre-space / hypre
Parallel solvers for sparse linear systems featuring multigrid methods.
- math-physics
- library
- hpc
- radiuss
34.stevengj / nlopt
library for nonlinear optimization, wrapping many algorithms for global and local, constrained or unconstrained, optimization
35.symengine / symengine
SymEngine is a fast symbolic manipulation library, written in C++
- math
- computer-algebra
- c-plus-plus
36.libtom / libtommath
LibTomMath is a free open source portable number theoretic multiple-precision integer library written entirely in C.
- mpi
- libtommath
- c
- math
- multi-precision
37.flame / blis
BLAS-like Library Instantiation Software Framework
- blis
- blas
- blas-libraries
- linear-algebra
- linear-algebra-library
- matrix-multiplication
- +8 more
39.hjwdzh / QuadriFlow
QuadriFlow: A Scalable and Robust Method for Quadrangulation
- quadriflow
- quad
- remeshing
- quadrangulation
- geometry
40.fo-dicom / fo-dicom
Fellow Oak DICOM for .NET, .NET Core, Universal Windows, Android, iOS, Mono and Unity
- dicom
- netcore
- medical
- medical-imaging
- dot-net
- c-sharp
- +4 more
41.NetTopologySuite / NetTopologySuite
A .NET GIS solution that is fast and reliable for the .NET platform.
- topology
- nts
- sfs
- c-sharp
- library
- jts
- +1 more
42.trilinos / Trilinos
Primary repository for the Trilinos Project
- snl-science-libs
- sandia-national-laboratories
- hpsf
- scientific-computing
- high-performance-computing
- c-plus-plus
- +2 more
43.mahmoodlab / CONCH
Vision-Language Pathology Foundation Model - Nature Medicine
- bioimage-analysis
- bioimage-informatics
- conch
- foundation-model
- health-informatics
- histopathology
- +9 more
45.UniMath / UniMath
This rocq library aims to formalize a substantial body of mathematics using the univalent point of view.
- coq
- mathematics
- unimath
- coq-library
- foundations
- rocq
- +1 more
46.usnistgov / fipy
FiPy is a Finite Volume PDE solver written in Python
- scientific-computing
- scientific-computing-with-python
- phase-field
- materials-science
- partial-differential-equations
- shared-memory-parallel
- +2 more
48.nasa / trick
Trick Simulation Environment. Trick provides a common set of simulation capabilities and utilities to build simulations automatically.
49.rsvp / fecon235
Notebooks for financial economics. Keywords: Jupyter notebook pandas Federal Reserve FRED Ferbus GDP CPI PCE inflation unemployment wage income debt Case-Shiller housing asset portfolio equities SPX bonds TIPS rates currency FX euro EUR USD JPY yen XAU gold Brent WTI oil Holt-Winters time-series forecasting statistics econometrics
- jupyter-notebook
- pandas
- federal-reserve
- gdp
- inflation
- housing
- +14 more
50.brandon-rhodes / pyephem
Scientific-grade astronomy routines for Python
51.firedrakeproject / firedrake
Firedrake is an automated system for the portable solution of partial differential equations using the finite element method (FEM)
52.rafat / wavelib
C Implementation of 1D and 2D Wavelet Transforms (DWT,SWT and MODWT) along with 1D Wavelet packet Transform and 1D Continuous Wavelet Transform.
- wavelets
- dwt
- continuous-wavelet-transform
- wavelet-packet-trees
- c
- cpp
53.anpa1200 / adversarygraph
Self-hosted AI-assisted CTI-to-detection workbench for ATT&CK mapping, IOC/CVE intelligence, Threat Radar, malware triage, Attack Simulation, and SIEM validation.
- cybersecurity
- docker
- fastapi
- llm
- mitre-attack
- react
- +14 more
54.samtools / htslib
C library for high-throughput sequencing data formats
- htslib
- bioinformatics
- sam
- bam
- cram
- vcf
- +2 more
55.PetteriAimonen / libfixmath
Cross Platform Fixed Point Maths Library
56.PaddlePaddle / Quantum
The repository host gives no description.
58.haddocking / pdb-tools
A dependency-free cross-platform swiss army knife for PDB files.
- python
- protein
- pdb
- bioinformatics
- structural-biology
- structural-bioinformatics
- +2 more
59.excessive / cpml
Cirno's Perfect Math Library: Just about everything you need for 2D/3D games. Hopefully.
60.biolink / biolink-model
Schema and generated objects for biolink data model and upper ontology
- biolink
- monarchinitiative
- gene-ontology
- datamodel
- standard
- specification
- +11 more
61.qhull / qhull
Qhull development for www.qhull.org -- Qhull 2020.2 (8.1-alpha1) at https://github.com/qhull/qhull/wiki
- qhull
- computational-geometry
- convex-hull
- delaunay-triangulation
- voronoi-diagram
- halfspace-intersection
- +3 more
62.dib-lab / khmer
In-memory nucleotide sequence k-mer counting, filtering, graph traversal and more
- dna
- k-mer
- python
- bloom-filter
- count-min-sketch
- graph-traversal
- +1 more
63.chebfun / chebfun
Chebfun: numerical computing with functions.
64.alphaville / optimization-engine
Nonconvex embedded optimization: code generation for fast real-time optimization + ROS support
- embedded-optimization
- nonconvex
- model-predictive-control
- rust-library
- rust
- rust-crate
- +14 more
65.MmgTools / mmg
open source software for bidimensional and tridimensional remeshing
- mesh
- mesh-adaptation
- anisotropic-mesh-adaptation
- isotropic-mesh-adaptation
- mesh-quality-improvement
- surface-improvement
- +11 more
66.ebassi / graphene
A thin layer of graphic data types
- graphics-library
- vector
- transformations
- matrix
- 3d-transformations
- c
- +4 more
67.xiaoyeli / superlu
Supernodal sparse direct solver. https://portal.nersc.gov/project/sparse/superlu/
68.rocq-community / fourcolor
Formal proof of the Four Color Theorem [maintainer=@ybertot]
- coq
- ssreflect
- mathcomp
- four-color-theorem
- coq-ci
69.sanderlab / scPerturb
scPerturb: A resource and a python/R tool for single-cell perturbation data
70.JuliaPhylo / PhyloNetworks.jl
PhyloNetworks: a julia package with utilities for phylogenetic networks
72.rbdl / rbdl
RBDL is a C++ library that contains some essential and efficient rigid body dynamics algorithms such as the Articulated Body Algorithm (ABA) for forward dynamics, Recursive Newton-Euler Algorithm (RNEA) for inverse dynamics, the Composite Rigid Body Algorithm (CRBA) for the efficient computation of the joint space inertia matrix and is also able to compute forward dynamics with external contact constraints and collision impulses. Furthermore it has some basic support for forward and inverse kinematics.
- articulated-body-algorithm
- inverse-dynamics
- forward-dynamics
- multi-body-dynamics
- inverse-kinematics
- robotics
73.Tronald / CoordinateSharp
A library designed to ease geographic coordinate format conversions, and determine sun/moon information in C#
- moon
- coordinates
- longitude
- latitude
- mgrs
- utm
- +13 more
74.bp-kelley / descriptastorus
Descriptor computation(chemistry) and (optional) storage for machine learning
75.microsoft / Quantum-NCArchived
Microsoft Quantum Computing Libraries for noncommercial use
- quantum-development-kit
- quantum
- qdk
- quantum-computing
- qsharp
- python
76.spamegg1 / Math-for-CS-solutions
Solutions to In-Class questions, Problem Sets and Exams of MIT Mathematics for Computer Science 2015 (same as 2019 Open Learning Library)
- calculus
- counting
- functions
- graph
- graph-theory
- induction
- +11 more
77.mapbox / wagyu
A general library for geometry operations of union, intersections, difference, and xor
- computational-geometry
- union
- intersection
- xor
- geometry
- difference
- +1 more
78.hpddm / hpddm
A framework for high-performance domain decomposition methods.
- c-plus-plus
- linear-algebra
- python
- fortran
- c
- freefem
- +4 more
79.JuliaGraphs / MetaGraphs.jl
Graph data structures with multiple heterogeneous metadata for Graphs.jl.
- graph
- graphs
- metadata
- juliagraphs
- datastructures
- data-structures
- +1 more
80.LigandPro / Matcha
Multi-stage Riemannian flow matching for physically valid molecular docking, with GNINA scoring, PoseBusters filtering, CLI inference, and benchmarks.
- alphafold3
- docking
- drug-design
- drug-discovery
- flowmatching
- gnina
- +8 more