1.RosettaCommons / RFD4-Proteina
Generative biopolymer design with rich conditioning.
+544 stars
from 1 · score 6.30
Trending repositories
Ranked by Attention Score: stars gained over the last 30 complete days
26 repositories by Attention Score · Oct 5, 2026 – Nov 3, 2026 (UTC)
2.heise3 / ExtremaRank
Native R and Python sample-deletion robustness for omics: candidate certificates, minimum deletion bounds, Bioconductor model refits and donor-level pseudobulk
- bioinformatics
- exact-optimization
- metabolomics
- paired-data
- proteomics
- python
- +14 more
+288 stars
from 1 · score 5.67
+120 stars
from 8,601 · score 4.80
4.deepchem / deepchem
Democratizing Deep-Learning for Drug Discovery, Quantum Chemistry, Materials Science and Biology
- drug-discovery
- quantum-chemistry
- deep-learning
- biology
- materials-science
- hacktoberfest
+96 stars
from 7,027 · score 4.57
+70 stars
from 14,856 · score 4.26
6.jwohlwend / boltz
Official repository for the Boltz biomolecular interaction models
- binding-prediction
- drug-discovery
- protein-structure
+59 stars
from 4,230 · score 4.09
+49 stars
from 3,070 · score 3.91
8.biopython / biopython
Official git repository for Biopython (originally converted from CVS)
- python
- bioinformatics
- genomics
- biopython
- protein
- protein-structure
- +3 more
+42 stars
from 5,215 · score 3.76
9.Biohub / esm
The repository host gives no description.
+37 stars
from 2,976 · score 3.64
+35 stars
from 1,863 · score 3.58
11.ClawBio / ClawBio
🦖 ClawBio - The first bioinformatics-native AI agent skill library. Local-first. Reproducible. Open. Free.
- ai-agents
- bioinformatics
- equity
- genomics
- local-first
- openclaw
- +2 more
+23 stars
from 1,149 · score 3.18
+22 stars
from 2,259 · score 3.14
13.scverse / scvi-tools
Deep probabilistic analysis of single-cell and spatial omics data
- scrna-seq
- variational-bayes
- variational-autoencoder
- cite-seq
- single-cell-genomics
- single-cell-rna-seq
- +4 more
+20 stars
from 1,700 · score 3.04
+19 stars
from 1,644 · score 3.00
15.aqlaboratory / openfold
Trainable, memory-efficient, and GPU-friendly PyTorch reproduction of AlphaFold 2
- pytorch
- protein-structure
- alphafold2
+14 stars
from 3,435 · score 2.71
16.evo-design / evo
Biological foundation modeling from molecular to genome scale
+14 stars
from 1,572 · score 2.71
17.RosettaCommons / RoseTTAFold
This package contains deep learning models and related scripts for RoseTTAFold
+13 stars
from 2,267 · score 2.64
18.instadeepai / nucleotide-transformer
Foundation Models for Genomics & Transcriptomics
- genomics
- deep-learning
- transformer
- dna
- foundation-models
- transcriptomics
- +1 more
+12 stars
from 922 · score 2.56
19.facebookresearch / esmArchived
Evolutionary Scale Modeling (esm): Pretrained language models for proteins
+9 stars
from 4,166 · score 2.30
20.kexinhuang12345 / DeepPurpose
A Deep Learning Toolkit for DTI, Drug Property, PPI, DDI, Protein Function Prediction (Bioinformatics)
- drug-repurposing
- deep-learning
- drug-target-interactions
- toolkit
- covid19
- virtual-screening
- +13 more
+9 stars
from 1,192 · score 2.30
21.chaidiscovery / chai-lab
Chai-1, SOTA model for biomolecular structure prediction
+8 stars
from 1,999 · score 2.20
22.samtools / htslib
C library for high-throughput sequencing data formats
- htslib
- bioinformatics
- sam
- bam
- cram
- vcf
- +2 more
+4 stars
from 953 · score 1.61
23.broadinstitute / cromwell
Scientific workflow engine designed for simplicity & scalability. Trivially transition between one off use cases to massive scale production environments
- workflow-execution
- workflow
- cloud
- hpc
- bioinformatics
- executor
- +7 more
+3 stars
from 1,080 · score 1.39
24.hail-is / hail
Cloud-native genomic dataframes and batch computing
- genetics
- vcf
- genomics
- gwas
- bioinformatics
- python
- +2 more
+3 stars
from 1,079 · score 1.39
25.bcbio / bcbio-nextgen
Validated, scalable, community developed variant calling, RNA-seq and small RNA analysis
+1 stars
from 1,029 · score 0.69
26.txWang / MOGONET
MOGONET (Multi-Omics Graph cOnvolutional NETworks) is a novel multi-omics data integrative analysis framework for classification tasks in biomedical applications.
+1 stars
from 188 · score 0.69